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Rabbit anti Parathyroid Hormone (PTH) Polyclonal Antibody
Rabbit anti Parathyroid Hormone (PTH) Polyclonal Antibody
- 中文名称：
- Rabbit anti Parathyroid Hormone (PTH) Polyclonal Antibody
- 英文名称：
- Rabbit anti Parathyroid Hormone (PTH) Polyclonal Antibody
- 品牌：
- AAA Biotech
- 品牌介绍：
- AAA Biotech专注于为全球生命科学研究提供高品质的蛋白质研究工具，核心产品包括经严格验证的抗体、重组蛋白及ELISA试剂盒。
- 货号：
- AAA71308
- 规格：
- 0.1 mg|2x0.1 mg|3x0.1 mg|4x0.1 mg|5x0.1 mg
- 保存建议：
- The antibodies are stable when stored at -20°C. The antibodies can be stored at 2°C - 8°C without detectable loss of activity. Avoid repeated freezing-thawing cycles.
- 货期：
- 6-8周
- 来源宿主：
- Rabbit
- 反应种属：
- Human
- 应用：
- WB (Western Blot), IP (Immunoprecipitation), IHC (Immunohistochemistry)
- 免责声明：
- *本产品仅供科研实验使用，不得用于临床诊断。*
- 其他：
克隆性:Polyclonal
同型:IgG
克隆号:N/A
特异性:This antibody recognizes ~11 kDa of human PTH Protein. It cross reacts to human. The other species are not tested.
纯度:Purified by Epitope Affinity Purification
形式：Supplied in sterile Phosphate buffered saline (pH7.2) containing antibody stabilizer.
浓度：N/A
- 说明书：
Parathyroid hormone (PTH), parathormone or parathyrin, is secreted by the chief cells of the parathyroid glands as a polypeptide. PTH elevates calcium level by dissolving the salts in bone and preventing their renal excretion. The PTH binds to the parathyroid hormone/parathyroid hormone-related peptide receptor and regulates blood calcium and phosphate levels. Excess protein, known as hyperparathyroidism, can result in hypercalcemia and kidney stones. Defective protein may lead to hypoparathyroidism, which can result in hypocalcemia and numbness. Parathyroid hormone (PTH) has been proved to play a pivotal role in maintaining myocardial contractility as well as effective natriuresis, and possible pathogenic mechanisms contributing to heart failure secondary to hypocalcemia and hypoparathyroidism. With the increased population of preosteoblastic lineages and the osteoblastic activation, Parathyroid hormone (PTH) drives anabolism in bone. Experiments have recently reported that PTH affects bone cells in a dual pathway – mediating osteoblastic (preosteoblastic) activities or osteocytic synthesis of sclerostin. Defects in PTH are a cause of familial isolated hypoparathyroidism (FIH), also called autosomal dominant hypoparathyroidism or autosomal dominant hypocalcemia. FIH is characterized by hypocalcemia and hyperphosphatemia due to inadequate secretion of parathyroid hormone. Symptoms are seizures, tetany, and cramps.
