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Mouse anti-Androgen Receptor Monoclonal Antibody
Mouse anti-Androgen Receptor Monoclonal Antibody
- 中文名称：
- Mouse anti-Androgen Receptor Monoclonal Antibody
- 英文名称：
- Mouse anti-Androgen Receptor Monoclonal Antibody
- 品牌：
- AAA Biotech
- 品牌介绍：
- AAA Biotech专注于为全球生命科学研究提供高品质的蛋白质研究工具，核心产品包括经严格验证的抗体、重组蛋白及ELISA试剂盒。
- 货号：
- AAA71319
- 规格：
- 0.1 mg|2x0.1 mg|3x0.1 mg|4x0.1 mg|5x0.1 mg
- 保存建议：
- The antibodies are stable for 12 months from date of receipt when stored at –20 degree C to –70 degree C. The antibodies can be stored at 2 degree C - 8 degree C for three month without detectable loss of activity. Avoid repeated freezing-thawing cycles.
- 货期：
- 6-8周
- 来源宿主：
- Mouse
- 反应种属：
- Human
- 应用：
- FCM/FACS (Flow Cytometry), IP (Immunoprecipitation), ELISA, IHC (Immunohistochemistry), WB (Western Blot)
- 免责声明：
- *本产品仅供科研实验使用，不得用于临床诊断。*
- 其他：
克隆性:Monoclonal
同型:IgG1 kappa
克隆号:[SPM335]
特异性:This antibody recognizes human Androgen Receptor protein. The other species was not tested.
纯度:The Mouse IgG is purified by Isotyping-specific Affinity Purification.
形式：This affinity purified antibody is supplied in sterile Phosphatebuffered saline (pH7.2) containing antibody stabilizer
浓度：N/A
- 说明书：
The androgen receptor belongs to the nuclear receptor subfamily 3 group C member 4 which is encoded by the Ar (also known as Andr, Nr3c4, Tfm) gene. Androgen receptor (AR) is a hormone-activated transcription regulator that plays important roles in normal prostate development and function, as well as in malignant prostate transformation. The binding of an androgenic hormone (testosterone or dihydrotestosterone) induces a conformational change in AR, resulting its dissociation from heat shock proteins and subsequent translocation from the cytosol to nucleus, where it dimerizes and mediates either transcription activation or repression in a target gene-specific manner. The androgen insensitivity syndrome (AIS) or testicular feminization (TFM) is caused by a mutation of the androgen receptor gene located on the X chromosome.
