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Rabbit anti DBF4 Polyclonal Antibody
Rabbit anti DBF4 Polyclonal Antibody
- 中文名称:
- Rabbit anti DBF4 Polyclonal Antibody
- 英文名称:
- Rabbit anti DBF4 Polyclonal Antibody
- 品牌:
- AAA Biotech
- 品牌介绍:
- AAA Biotech专注于为全球生命科学研究提供高品质的蛋白质研究工具,核心产品包括经严格验证的抗体、重组蛋白及ELISA试剂盒。
- 货号:
- AAA71334
- 规格:
- 0.1 mg|2x0.1 mg|3x0.1 mg|4x0.1 mg|5x0.1 mg
- 保存建议:
- The antibodies are stable when stored at -20°C to -70°C. The antibodies can be stored at 2°C-8°C for three month without detectable loss of activity. Avoid repeated freezing-thawing cycles.
- 货期:
- 6-8周
- 来源宿主:
- Rabbit
- 反应种属:
- Human, Rat, Mouse
- 应用:
- WB (Western Blot), IP (Immunoprecipitation), IHC (Immunohistochemistry), ELISA
- 免责声明:
- *本产品仅供科研实验使用,不得用于临床诊断。*
- 其他:
克隆性:Polyclonal
同型:IgG
克隆号:N/A
特异性:This antibody recognizes ~77 kDa of DBF4 protein. It cross reacts to human, mouse and rat. The other species are not tested.
纯度:Purified by Epitope Affinity Purification
形式:Supplied in sterile Phosphate buffered saline (pH7.2) containing antibody stabilizer.
浓度:N/A
- 说明书:
The human DBF4/ASK protein contains a putative site for phosphorylation by CDK, PEST protease cleavage sites, nuclear localization signals and a short-looped zinc finger-like domain. DBF4 interacts physically with CDC7 and MCM2 as a cyclin-like regulatory subunit of mammalian CDC7, thus it plays a key role in the regulation of DNA replication during the cell cycle in all eukaryotes. The DBF4/ASK is also identified as a novel determinant for melanoma development. The up-regulation of ASK/DBF4 is a novel molecular determinant with prognostic relevance that confers a proliferative advantage in melanoma.