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Mouse anti BRCA1 Monoclonal Antibody
Mouse anti BRCA1 Monoclonal Antibody
- 中文名称：
- Mouse anti BRCA1 Monoclonal Antibody
- 英文名称：
- Mouse anti BRCA1 Monoclonal Antibody
- 品牌：
- AAA Biotech
- 品牌介绍：
- AAA Biotech专注于为全球生命科学研究提供高品质的蛋白质研究工具，核心产品包括经严格验证的抗体、重组蛋白及ELISA试剂盒。
- 货号：
- AAA71341
- 规格：
- 0.1 mg|2x0.1 mg|3x0.1 mg|4x0.1 mg|5x0.1 mg
- 保存建议：
- The antibodies are stable for 12 months from date of receipt when stored at -20°C to -70°C. The antibodies can be stored at 2-8°C for three months without detectable loss of activity. Avoid repeated freezing-thawing cycles.
- 货期：
- 6-8周
- 来源宿主：
- Mouse
- 反应种属：
- Human
- 应用：
- IHC (Immunohistochemistry), IP (Immunoprecipitation), ELISA, WB (Western Blot)
- 免责声明：
- *本产品仅供科研实验使用，不得用于临床诊断。*
- 其他：
克隆性:Monoclonal
同型:IgG1κ
克隆号:[MS110]
特异性:Recognizes ~220 kDa of human BRCA1 protein. The other species are not tested.
纯度:Affinity Purification according to the isotyping
形式：Supplied in sterile Phosphate-buffered saline (pH 7.2) containing antibody stabilizer
浓度：N/A
- 说明书：
BRCA1 is a nuclear phosphoprotein that plays a role in maintaining genomic stability and it also acts as a tumor suppresor. The protein combines with other tumor suppressors, DNA damage sensors, and signal transducers to form a large multi-subunit protein complex known as the BRCA1-associated genome surveillance complex (BASC). It plays a role in transcription, DNA repair of double-stranded breaks, and recombination. Mutations in this gene are responsible for approximately 40% of inherited breast cancers and more than 80% of inherited breast and ovarian cancers. BRCA1 is widely expressed in lymph nodes, testis, colon and other tissues.
