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Rabbit anti eNOS antibody
Rabbit anti eNOS antibody
- 中文名称:
- Rabbit anti eNOS antibody
- 英文名称:
- Rabbit anti eNOS antibody
- 品牌:
- AAA Biotech
- 品牌介绍:
- AAA Biotech专注于为全球生命科学研究提供高品质的蛋白质研究工具,核心产品包括经严格验证的抗体、重组蛋白及ELISA试剂盒。
- 货号:
- AAA71381
- 规格:
- 0.1 mg|2x0.1 mg|3x0.1 mg|4x0.1 mg|5x0.1 mg
- 保存建议:
- The antibodies are stable for 12 months from date of receipt when stored at -20°C to -70°C. The antibodies can be stored at 2°C - 8°C for three month without detectable loss of activity. Avoid repeated freezing-thawing cycles.
- 货期:
- 6-8周
- 来源宿主:
- Rabbit
- 反应种属:
- Human, Rat, Mouse, Dog, Pig, Cow
- 应用:
- IHC (Immunohistochemistry), WB (Western Blot), ELISA
- 免责声明:
- *本产品仅供科研实验使用,不得用于临床诊断。*
- 其他:
克隆性:N/A
同型:N/A
克隆号:N/A
特异性:This antibody only recognizes ~130 kDa of human eNOS. It does not detect human inducible NOS or rat brain NOS. It also reacts with mouse and rat eNOS protein. The other species are not tested.
纯度:The Rabbit IgG is purified by Epitope Affinity Purification.
形式:This affinity purified antibody is supplied in sterile phosphatebuffered saline (pH7.2) containing antibody stabilizer
浓度:N/A
- 说明书:
NOS catalyzes the oxidization of L-arginine to produce L-citrulline and NO. Nitric oxide (NO) is an inorganic, gaseous free radical that carries a variety of messages between cells. Vasorelaxation, neurotransmission and cytotoxicity can all be enhanced through cellular response to NO. NO production is mediated by members of the nitric oxide synthase (NOS) family. There are three types of NOS: two constitutive isoforms, brain or neuronal NOS (b or nNOS, type I) & endothelial cell NOS (eNOS, type III), and one inducible isoform (iNOS, type II). iNOS is found in a variety of cell types including macrophages, hepatocytes, synoviocytes, and smooth muscle cells. Cytokines such as interferon-gamma (IFN), tumor necrosis factor (TNF), interleukin-1 and -2, and lipopolysaccarides (LPS) cause an increase in iNOS mRNA, protein, and activity levels. The phosphorylation of eNOS by Protein kinase C was associated with an increase in NO production.