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Rabbit anti SOX-9 (pSer181), Phospho-specific
Rabbit anti SOX-9 (pSer181), Phospho-specific
- 中文名称：
- Rabbit anti SOX-9 (pSer181), Phospho-specific
- 英文名称：
- Rabbit anti SOX-9 (pSer181), Phospho-specific
- 品牌：
- AAA Biotech
- 品牌介绍：
- AAA Biotech专注于为全球生命科学研究提供高品质的蛋白质研究工具，核心产品包括经严格验证的抗体、重组蛋白及ELISA试剂盒。
- 货号：
- AAA71414
- 规格：
- 0.1 mg|2x0.1 mg|3x0.1 mg|4x0.1 mg|5x0.1 mg
- 保存建议：
- The antibodies are stable for 12 months from date of receipt when stored at -20 degree C to -70 degree C. The antibodies can be stored at 2 degree C-8 degree C for three month without detectable loss of activity. Avoid repeated freezing-thawing cycles.
- 货期：
- 6-8周
- 来源宿主：
- Rabbit
- 反应种属：
- Human, Rat, Mouse, Chicken, Bovine, Canine
- 应用：
- IP (Immunoprecipitation), IHC (Immunohistochemistry), WB (Western Blot), ELISA
- 免责声明：
- *本产品仅供科研实验使用，不得用于临床诊断。*
- 其他：
克隆性:N/A
同型:N/A
克隆号:N/A
特异性:This antibody recognizes ~56 kDa of human SOX-9 protein at the phosphorylation site of Ser181. It does not cross react to non-phospho SOX-9. It also reacts with mouse and rat. The other species are not tested.
纯度:The Rabbit IgG is purified by Site-specific Epitope Affinity Purification.
形式：This affinity purified antibody is supplied in sterile Tris-buffered saline (pH7.2) containing antibody stabilizer
浓度：Size: 100 ug/200 ul
- 说明书：
The SOX9 is a member of the SOX [Sry-related high-mobility group (HMG) box] family of HMG DNA-binding domain transcription factors and is required for the development and differentiation of multiple cell lineages. SOX9 is expressed in primary prostate cancers in vivo, at a higher frequency in recurrent prostate cancer and in prostate cancer cell lines (LNCaP, CWR22, PC3, and DU145). It has been reported that the cAMP/PKA stimulation induces SOX-9 nuclear translocation via facilitating its nuclear import by the phosphorylation of SOX-9 at Ser64 and Ser181. SOX9 in prostate basal cells supports the development and maintenance of the luminal epithelium and that a subset of prostate cancer cells may escape basal cell requirements through SOX9 expression.
