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Integrin beta1 (Extracellular region) M0411 Antibody
Integrin beta1 (Extracellular region) M0411 Antibody
- 中文名称:
- Integrin beta1 (Extracellular region) M0411 Antibody
- 英文名称:
- Integrin beta1 (Extracellular region) M0411 Antibody
- 品牌:
- AAA Biotech
- 品牌介绍:
- AAA Biotech专注于为全球生命科学研究提供高品质的蛋白质研究工具,核心产品包括经严格验证的抗体、重组蛋白及ELISA试剂盒。
- 货号:
- AAA71651
- 规格:
- 0.1 mL|2x0.1 mL|3x0.1 mL|4x0.1 mL|5x0.1 mL
- 保存建议:
- Store at -20 degree C. Stable for 1 year.
- 货期:
- 6-8周
- 来源宿主:
- Mouse
- 反应种属:
- Human
- 应用:
- IP (Immunoprecipitation), ICC (Immunocytochemistry), ELISA, WB (Western Blot)
- 免责声明:
- *本产品仅供科研实验使用,不得用于临床诊断。*
- 其他:
克隆性:Monoclonal
同型:IgG2a
克隆号:[M041]
特异性:Clone M0411 detects 120-150kDa* bands corresponding to Integrin beta1 on SDS-PAGE immunoblots of native human A431, LNCaP, MCF7, and NCI-H446 cell lysates, as well as human lung tissue. The antibody does not detect the denatured form of Integrin beta1. Clone M0411 can be used in western blot, immunocytochemistry, and immunoprecipitation, as well as for ELISA detection when paired with Integrin beta1 IM0041 as the capture antibody.
纯度:Protein G chromatography
形式:Mouse monoclonal antibody purified with protein G chromatography is supplied in 100ul phosphate-buffered saline, 50% glycerol, 1mg/ml BSA, and 0.05% sodium azide.
浓度:N/A
- 说明书:
Integrins are cell adhesion molecules that can mediate bidirectional transfer of signals across the plasma membrane. The cytoplasmic domains of integrin family members interact with components of the signal transduction apparatus within cells. Integrin receptors contain noncovalently associated alpha and beta subunits that consist of a large extracellular region (the ligand-binding domain), a short transmembrane region, and a cytoplasmic domain of varying length. In mammals, at least 17 alpha subunits and 8 beta subunits have been identified and these proteins can heterodimerize to form at least 22 different receptors. The beta1 subfamily includes 12 distinct integrin proteins that bind to different extracellular matrix molecules. Integrin beta1 has been implicated in various activities including embryonic development, blood vessel, skin, bone, and muscle formation, as well as tumor metastasis and angiogenesis.