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alpha-Tubulin (C-terminus) Antibody
alpha-Tubulin (C-terminus) Antibody
- 中文名称：
- alpha-Tubulin (C-terminus) Antibody
- 英文名称：
- alpha-Tubulin (C-terminus) Antibody
- 品牌：
- AAA Biotech
- 品牌介绍：
- AAA Biotech专注于为全球生命科学研究提供高品质的蛋白质研究工具，核心产品包括经严格验证的抗体、重组蛋白及ELISA试剂盒。
- 货号：
- AAA71719
- 规格：
- 0.1 mL|2x0.1 mL|3x0.1 mL|4x0.1 mL|5x0.1 mL
- 保存建议：
- Store at -20 degree C. Stable for 1 year.
- 货期：
- 6-8周
- 来源宿主：
- Mouse
- 反应种属：
- Human, Rat, Mouse
- 应用：
- IHC (Immunohistochemistry), ICC (Immunocytochemistry), IP (Immunoprecipitation), ELISA, WB (Western Blot)
- 免责声明：
- *本产品仅供科研实验使用，不得用于临床诊断。*
- 其他：
克隆性:Monoclonal
同型:IgG1
克隆号:[DM1A]
特异性:The antibody detects a 55kDa* protein corresponding to the molecular mass of alpha-Tubulin on SDS-PAGE immunoblots of human, rat, and mouse cells and tissues.
纯度:Protein A chromatography
形式：Mouse monoclonal antibody purified with protein A chromatography is supplied in 100ul phosphate-buffered saline, 50% glycerol, 1mg/ml BSA, and 0.05% sodium azide.
浓度：N/A
- 说明书：
Microtubules (MTs) are cytoskeletal elements that play an essential role in cell division and cytoplasmic organization. MTs are dynamic polymers of a/beta-Tubulin heterodimers. At least two populations of MTs, called dynamic and stable according to their rates of turnover, are readily distinguishable in cells. The proteins associated with MTs (MAPs) are among the best-known factors that regulate MT dynamics and stability. In addition, a variety of different post-translational modifications may also regulate MT dynamics and stability. Phosphorylation is one of these modifications and it can occur on serine, threonine, and tyrosine residues in alpha- and beta-Tubulin isoforms. Multiple kinases can phosphorylate Ser-444 at the C-terminus of betaIII-Tubulin in vitro, and unphosphorylated Ser-444 may be an early marker for cells of neuronal lineage. Cdk1 can phosphorylate Ser-172 in beta-Tubulin during mitosis and this may impair tubulin incorporation into microtubules. In alpha-tubulin, PKC can phosphorylate Ser-165 leading to increased cell motility in human breast cells.
