Anti-MUC1 [12D10]-Anti-MUC1 [12D10]-一抗检测抗体 - 北京博蕾德生物科技有限公司

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: Anti-MUC1 [12D10]

Anti-MUC1 [12D10]

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中文名称：: Anti-MUC1 [12D10]

英文名称：: Anti-MUC1 [12D10]

品牌：: AAA Biotech

品牌介绍：: AAA Biotech专注于为全球生命科学研究提供高品质的蛋白质研究工具，核心产品包括经严格验证的抗体、重组蛋白及ELISA试剂盒。

货号：: AAA72325

规格：: 0.2 mg|2x0.2 mg|3x0.2 mg|4x0.2 mg|5x0.2 mg

保存建议：: Store at 4 degree C for up to 3 months. For longer storage, aliquot and store at -20 degree C.

货期：: 6-8周

来源宿主：: N/A

反应种属：: Human

应用：: SPR (Surface Plasmon Resonance), FCM/FACS (Flow Cytometry), ELISA

免责声明：: *本产品仅供科研实验使用，不得用于临床诊断。*

其他：: 克隆性:N/A
同型:Mouse IgG1 kappa
克隆号:[12D10]
特异性:This antibody is specific for the unsubstituted O-6 position of the Neu5Ac residue of MUC1. The alpha subunit of MUC1 has cell adhesive properties. Can act both as an adhesion and an anti-adhesion protein. May provide a protective layer on epithelial cells against bacterial and enzyme attack. The beta subunit of MUC-1 contains a C-terminal domain which is involved in cell signaling, through phosphorylations and protein-protein interactions. Modulates signaling in ERK, SRC and NF-kappa-B pathways. In activated T-cells, influences directly or indirectly the Ras/MAPK pathway. Promotes tumor progression. Regulates TP53-mediated transcription and determines cell fate in the genotoxic stress response. Binds, together with KLF4, the PE21 promoter element of TP53 and represses TP53 activity.
纯度:Purified. Protein A affinity purified
形式：PBS with 0.02% Proclin 300.
浓度：1mg/ml

说明书：

This antibody was raised by immunizing female Balb/c mice with MUC1 antigen.
. In this study, using an MUC1 glycopeptide library, we established two novel anti-MUC1 monoclonal antibodies (1B2 and 12D10) with designed carbohydrate specificities.

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