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alpha-II-Spectrin/alpha-Fodrin
alpha-II-Spectrin/alpha-Fodrin
- 中文名称:
- alpha-II-Spectrin/alpha-Fodrin
- 英文名称:
- alpha-II-Spectrin/alpha-Fodrin
- 品牌:
- AAA Biotech
- 品牌介绍:
- AAA Biotech专注于为全球生命科学研究提供高品质的蛋白质研究工具,核心产品包括经严格验证的抗体、重组蛋白及ELISA试剂盒。
- 货号:
- AAA76732
- 规格:
- 0.1 mL|2x0.1 mL|3x0.1 mL|4x0.1 mL|5x0.1 mL
- 保存建议:
- Antibody can also be aliquotted and stored frozen at -20 degree C in a manual defrost freezer for sixmonths without detectable loss of activity. The antibody can be stored at 2 degree - 8 degree C for 1 month without detectable loss of activity. Avoid repeated freeze-thaw cycles.
- 货期:
- 6-8周
- 来源宿主:
- Rabbit
- 反应种属:
- Human, Mouse, Rat, Bovine
- 应用:
- IF (Immunofluorescence), IHC (Immunohistochemistry), WB (Western Blot), ICC (Immunocytochemistry)
- 免责声明:
- *本产品仅供科研实验使用,不得用于临床诊断。*
- 其他:
克隆性:Polyclonal
同型:Rabbit IgG
克隆号:N/A
特异性:N/A
纯度:N/A
形式:Liquid. Supplied as an aliquot of serum plus 5mM NaN3
浓度:N/A
- 说明书:
Spectrin family molecules are important high molecular weight components of the submembranous cytoskeleton of eukaryotic cells. These proteins were isolated originally from lysed red blood cell membrane preparations which were named "ghosts", which gave rise to the name spectrin. They function as major components of the membraneous cytoskeleton, mediating interactions between integral membrane proteins, actin and many other cellular components. This antibody binds specifically to alphaII-spectrin, also known as non-erythroid spectrin or fodrin. In the CNS this protein is expressed only in neurons and so the antibody can be used to reveal the submembranous neuronal cytoskeleton in IF, ICC and IHC.
It was made against the recombinant human protein construct derived from the C-terminus of alphaII-spectrin comprising the C-terminal 14 spectrin repeats, specifically amino acids 676-2447. This antibody can be used to study alphaII-spectrin on western blots and to visualize the neuronal plasma membrane cytoskeleton in cells in culture and sectioned material.