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HSC70/HSP73 monoclonal antibody (1B5) (biotin conjugate)
HSC70/HSP73 monoclonal antibody (1B5) (biotin conjugate)
- 中文名称：
- HSC70/HSP73 monoclonal antibody (1B5) (biotin conjugate)
- 英文名称：
- HSC70/HSP73 monoclonal antibody (1B5) (biotin conjugate)
- 品牌：
- AAA Biotech
- 品牌介绍：
- AAA Biotech专注于为全球生命科学研究提供高品质的蛋白质研究工具，核心产品包括经严格验证的抗体、重组蛋白及ELISA试剂盒。
- 货号：
- AAA76985
- 规格：
- 0.05 mg|2x0.05 mg|3x0.05 mg|4x0.05 mg|5x0.05 mg
- 保存建议：
- Long term storage: -20 degree C
Short term storage: 4 degree C
Avoid freeze/thaw cycles.
- 货期：
- 6-8周
- 来源宿主：
- Rat
- 反应种属：
- Human, Mouse, Rat, Bovine, Chicken, Dog, Guinea pig, Hamster, Monkey, Porcine, Rabbit, Sheep
- 应用：
- EM (Electron Microscopy), WB (Western Blot), IP (Immunoprecipitation), IHC (Immunohistochemistry), ICC (Immunocytochemistry), FCM/FACS (Flow Cytometry), ELISA
- 免责声明：
- *本产品仅供科研实验使用，不得用于临床诊断。*
- 其他：
克隆性:Monoclonal
同型:IgG2b
克隆号:[1B5]
特异性:Recognizes human, mouse, rat, bovine, dog, chicken, guinea pig, hamster, monkey, pig, rabbit and sheep HSC70 (HSP73). Detects a band of ~73kDa by Western blot.
纯度:Protein G affinity purified.
形式：Liquid. In PBS, pH 7.2, containing 0.09% sodium azide.
浓度：N/A
- 说明书：
The Hsp70 family of heat shock protiens contains multiple homologs ranging in size from 66-78 kDa, and are the eukaryotic equivalents of the bacterial DnaK. The most studied Hsp70 members include the cytosolic stress-induced Hsp70 (Hsp72), the constitutive cytosolic Hsc70 (Hsp73), and the ER-localized BiP (Grp78). Hsp70 family members contain highly conserved N-terminal ATP-ase and C-terminal protein binding domains. Binding of peptide to Hsp70 is assisted by Hsp40, and stimulates the inherent ATPase activity of Hsp70, facilitating ATP hydrolysis and enhanced peptide binding. Hsp70 nucleotide exchange and substrate binding coordinates the folding of newly synthesized proteins, the re-folding of misfolded or denatured proteins, coordinates trafficking of proteins across cellular membranes, inhibits protein aggregation, and targets the degradation of proteins via the proteasomal pathway.
