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Rabbit anti Desmin K5
Rabbit anti Desmin K5
- 中文名称:
- Rabbit anti Desmin K5
- 英文名称:
- Rabbit anti Desmin K5
- 品牌:
- AAA Biotech
- 品牌介绍:
- AAA Biotech专注于为全球生命科学研究提供高品质的蛋白质研究工具,核心产品包括经严格验证的抗体、重组蛋白及ELISA试剂盒。
- 货号:
- AAA77635
- 规格:
- 0.25 mL|2x0.25 mL|3x0.25 mL|4x0.25 mL|5x0.25 mL
- 保存建议:
- The antibody is shipped at ambient temperature and may be stored at +4°C. For prolonged storage prepare appropriate aliquots and store at or below -20°C. Prior to use, an aliquot is thawed slowly in the dark at ambient temperature, spun down again and used to prepare working dilutions by adding sterile phosphate buffered saline (PBS, pH 7.2). Repeated thawing and freezing should be avoided. Working dilutions should be stored at +4°C, not refrozen, and preferably used the same day. If a slight precipitation occurs upon storage, this should be removed by centrifugation. It will not affect the performance or the concentration of the product.
- 货期:
- 6-8周
- 来源宿主:
- Rabbit
- 反应种属:
- Bovine, Chicken, Caprine, Hamster, Human, Mouse, Rat, Zebrafish
- 应用:
- WB (Western Blot), IHC (Immunohistochemistry), IHC (Immunohistochemistry)
- 免责声明:
- *本产品仅供科研实验使用,不得用于临床诊断。*
- 其他:
克隆性:Polyclonal
同型:N/A
克隆号:N/A
特异性:K5 reacts exclusively with desmin, which is expressed in smooth and striated muscle cells and their tumors.
纯度:N/A
形式:Each vial contains 250 ul Rabbit polyclonal antiSerum containing 0.09% sodium azide.
浓度:N/A
- 说明书:
Desmin is a 53 kDa intermediate filament protein and exhibits a high degree of tissue specificity, its expression being predominantly confined to all types of muscle cells (cardiac, skeletal and smooth muscle). Regulation of desmin expression is stage and tissue-specific, since it is induced during terminal development and muscle cell differentiation. In skeletal en cardiac muscle cells desmin is localized in the Z-disk region and at the intercalated disk. The expression pattern of desmin in smooth muscle is much more heterogenous. Coexpression of desmin and vimentin has been observed in tumors derived from muscle tissue, i.e. rhabdomyosarcomas and leiomyosarcomas. Furthermore, during myocard dysfunction dramatic changes in the distribution of desmin have been observed.