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Goat anti Human C3c, conjugated with FITC
Goat anti Human C3c, conjugated with FITC
- 中文名称：
- Goat anti Human C3c, conjugated with FITC
- 英文名称：
- Goat anti Human C3c, conjugated with FITC
- 品牌：
- AAA Biotech
- 品牌介绍：
- AAA Biotech专注于为全球生命科学研究提供高品质的蛋白质研究工具，核心产品包括经严格验证的抗体、重组蛋白及ELISA试剂盒。
- 货号：
- AAA77661
- 规格：
- 1 mL|2x1 mL|3x1 mL|4x1 mL|5x1 mL
- 保存建议：
- The lyophilized conjugate is shipped at ambient temperature and may be stored at +4 degree C; prolonged storage ator below -20 degree C. It is reconstituted by adding 1 ml sterile distilled water, spun down to remove insolubleparticles, divided into small aliquots, frozen and stored at or below -20 degree C. Prior to use, an aliquot is thawedslowly in the dark at ambient temperature, spun down again and used to prepare working dilutions by addingsterile phosphate buffered saline (PBS, pH 7.2). Repeated thawing and freezing should be avoided. Workingdilutions should be stored at +4°C, not refrozen, and preferably used the same day. If a slight precipitationoccurs upon storage, this should be removed by centrifugation. It will not affect the performance of theimmunoconjugate. Lyophilized at +4 degree C--at least 10 years. Reconstituted at or below -20 degree C--3-5 years.Reconstituted at +4 degree C--7 days
- 货期：
- 6-8周
- 来源宿主：
- Goat
- 反应种属：
- Human
- 应用：
- IF (Immunofluorescence), IHC (Immunohistochemistry), ICC (Immunocytochemistry), ELISA
- 免责声明：
- *本产品仅供科研实验使用，不得用于临床诊断。*
- 其他：
克隆性:Polyclonal
同型:N/A
克隆号:N/A
特异性:Fluorescein isothiocyanate-conjugated IgG fraction of polyclonal Goat antiSerum to C3c fragment of Human complement factor C3
纯度:N/A
形式：N/A
浓度：N/A
- 说明书：
Background:In immunoelectrophoresis against fresh human serum, a single precipitin line is obtained in the beta-1 region representing native C3. Against serum containing partly activated C3, a precipitin line is obtained which extends from the beta-1 into the alpha-2 region, demonstrating a gradient. In old serum containing totally activated C3 a single precipitin line in the alpha-2 region is obtained. Antisera to C3c cab also react with the fragments C3b, C3bi and smaller fragments, since they all carry antigenic determinants of the C3c domain. The product does not react with any other proteins component of human serum or plasma. The fluorescent immunoconjugate to human C3c is used to determine the presence and pattern of C3 in tissue lesions using immunohistochemical staining techniques. Locally deposited immune complexes in tissue usually contain complement, pointing to activation of the classical pathway. Complement activation in vivo implies active disease and may contribute to the elicitation of the pathogenesis and he extent of tissue destruction. Sometimes the identification can be based on directly on laboratory findings. This immunoconjugate is not prediluted. The optimum working dilution of each conjugate should be established by titration before being used. Excess labelled antibody must be avoided because it may cause high unspecific background staining and interfere with the specific signal.
