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Cardiac Myosin Heavy Chain Mouse Monoclonal (3-48_G5C7)
Cardiac Myosin Heavy Chain Mouse Monoclonal (3-48_G5C7)
- 中文名称：
- Cardiac Myosin Heavy Chain Mouse Monoclonal (3-48_G5C7)
- 英文名称：
- Cardiac Myosin Heavy Chain Mouse Monoclonal (3-48_G5C7)
- 品牌：
- AAA Biotech
- 品牌介绍：
- AAA Biotech专注于为全球生命科学研究提供高品质的蛋白质研究工具，核心产品包括经严格验证的抗体、重组蛋白及ELISA试剂盒。
- 货号：
- AAA77840
- 规格：
- 5 mg|2x5 mg|3x5 mg|4x5 mg|
- 保存建议：
- Lyophilized antibody can be kept at 4 degree C for up to 3 months and should be kept at-20 degree C for long-term storage.
To avoid freeze-thaw cycles, reconstituted antibody should be aliquoted before freezing for short-term storage (-20 degree C) or for long-term storage (-80 degree C).
For maximum recovery of product centrifuge the original vial prior to removing the cap. Further dilutions can be made in assay buffer.
- 货期：
- 6-8周
- 来源宿主：
- Mouse
- 反应种属：
- Human, Rat, Mouse
Predicted: Canine, Bovine and Rabbit
- 应用：
- IHC (Immunohistochemistry), IF (Immunofluorescence), WB (Western Blot), ELISA
- 免责声明：
- *本产品仅供科研实验使用，不得用于临床诊断。*
- 其他：
克隆性:Monoclonal
同型:IgG1 kappa
克隆号:[3-48]
特异性:This antibody recognizes alpha and beta type heavy chains of light meromyosin fragments (LMM) of cardiac myosin heavy chains. It also reacts with LMM fragments of cardiac myosin and beta heavy chain of slow human skeletal muscle. The antibody does not crossreact with human myosin light chains.
纯度:N/A
形式：Lyophilized protein G purified in PBS pH7.4 (Full IgG)
浓度：N/A
- 说明书：
Myosin is a highly conserved, ubiquitously expressed protein that hydrolyzes ATR and this reaction provides the energy required for muscle contraction that interacts with actin to generate the force for cellular movements. It is a hexameric protein composed of four light chains and two heavy chains, each containing an actin-binding site and an ATP hydrolysis site. The heavy chains are encoded by the MYH gene family and were first isolated from a human fetal skeletal muscle and are the major determinant in the speed of contraction of skeletal muscle. Cardiac myosin exists as two isoforms in humans, Alpha-cardiac myosins and beta-cardiac myosins. These two isoforms are expressed in different amounts in the human heart. Beta-cardiac myosin s the predominant form during normal physiology while the alpha-isoform contributes for approximately 7% of the total myosin. Mutations of the MYH genes are associated with several different dilated and hypertrophic cardiomyopathies.
