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mAb anti-human promyelocytic leukemia protein (PML)
mAb anti-human promyelocytic leukemia protein (PML)
- 中文名称:
- mAb anti-human promyelocytic leukemia protein (PML)
- 英文名称:
- mAb anti-human promyelocytic leukemia protein (PML)
- 品牌:
- AAA Biotech
- 品牌介绍:
- AAA Biotech专注于为全球生命科学研究提供高品质的蛋白质研究工具,核心产品包括经严格验证的抗体、重组蛋白及ELISA试剂盒。
- 货号:
- AAA77899
- 规格:
- 0.1 mg|0.5 mg|2x0.5 mg|3x0.5 mg|4x0.5 mg
- 保存建议:
- 储存在-20摄氏度
- 货期:
- 6-8周
- 来源宿主:
- Mouse
- 反应种属:
- Human. Others not tested
- 应用:
- WB (Western Blot)
- 免责声明:
- *本产品仅供科研实验使用,不得用于临床诊断。*
- 其他:
克隆性:Monoclonal
同型:IgG1,k
克隆号:[B3E9]
特异性:This antibody recognizes normal PML proteins of lower molecular weight, and also recognizes the high molecular weight PML/RARalpha chimeric protein in promyelocytic leukemia patients.
Promyeloctic Leukemia (PML) [Ring Finger Domain]
纯度:Protein G affinity purified
形式:Lyophilized in pH 7.4, 0.01M PBS.
浓度:N/A
- 说明书:
Acute promyelocytic leukemia (PML) is a type of acute myelogenous leukemia that is caused by the translocation of the retinoic acid receptor alpha (RAR?) gene at chromosome 17 to the promyelocytic leukemia (PML) gene at chromosome 15. The chimeric protein (PML/RAR?) has a higher molecular weight than normal PML protein. The altered proteins block DNA transcription and differentiation of granulocytes, reduce the production of red cells and platelets, consequently, resulting in anemia and thrombocytopenia.