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mAb anti-Human TNF-a
mAb anti-Human TNF-a
- 中文名称：
- mAb anti-Human TNF-a
- 英文名称：
- mAb anti-Human TNF-a
- 品牌：
- AAA Biotech
- 品牌介绍：
- AAA Biotech专注于为全球生命科学研究提供高品质的蛋白质研究工具，核心产品包括经严格验证的抗体、重组蛋白及ELISA试剂盒。
- 货号：
- AAA77918
- 规格：
- 0.1 mg|0.5 mg|2x0.5 mg|3x0.5 mg|4x0.5 mg
- 保存建议：
- 储存在-20摄氏度
- 货期：
- 6-8周
- 来源宿主：
- Mouse
- 反应种属：
- Human. Other species not tested
- 免责声明：
- *本产品仅供科研实验使用，不得用于临床诊断。*
- 其他：
克隆性:Monoclonal
同型:IgG1, k
克隆号:[C2A7]
特异性:This antibody recognizes recombinant human TNF-?. Reactivity with natural TNF-? is not tested.
纯度:Protein G affinity purified
形式：Lyophilized from a solution in 0.01M PBS, pH 7.0
浓度：N/A
- 说明书：
Tumor Necrosis Factor alpha (TNF-?) is a multifunctional pro-inflammatory cytokine, mainly secreted by activated macrophages. It is implicated with a variety of biological procedures including systemic inflammation, cell proliferation, apoptosis, lipid metabolism, and coagulation. The pleiotropic attribute of TNF-? regulation is associated with its ability to trigger multiple signalling pathways through its receptors, TNFR1 (p55) and TNFR2 (p75). TNF-? not only contributes to the immune response to bacterial, fungal, viral and parasitic invasions, but also functions in tissue remodeling, autoimmune-diseases and the necrosis of specific tumors. TNF-? hyper-expression in response to some bacterial components such as LPS can cause life threatening septic shock. Recombinant TNF-?, in combination with chemotherapy, has been applied for treatment of soft sarcomas, melanomas and other irresectable tumors. Anti-TNF-? therapy has been used for treatment of rheumatoid arthritis.
