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mAb anti-Human GP IIb/IIIa
mAb anti-Human GP IIb/IIIa
- 中文名称:
- mAb anti-Human GP IIb/IIIa
- 英文名称:
- mAb anti-Human GP IIb/IIIa
- 品牌:
- AAA Biotech
- 品牌介绍:
- AAA Biotech专注于为全球生命科学研究提供高品质的蛋白质研究工具,核心产品包括经严格验证的抗体、重组蛋白及ELISA试剂盒。
- 货号:
- AAA77934
- 规格:
- 0.1 mg|0.5 mg|2x0.5 mg|3x0.5 mg|4x0.5 mg
- 保存建议:
- Store at -20°C
- 货期:
- 6-8周
- 来源宿主:
- Mouse
- 反应种属:
- Human. Others not tested
- 应用:
- WB (Western Blot), ELISA
- 免责声明:
- *本产品仅供科研实验使用,不得用于临床诊断。*
- 其他:
克隆性:Monoclonal
同型:IgG1, kappa
克隆号:[71]
特异性:The mAb reacts with human platelet.
纯度:Protein G affinity purified
形式:Lyophilized from a solution in 0.01M PBS, pH 7.2
浓度:N/A
- 说明书:
Description: Mouse monoclonal antibody to human platelet membrane glycoprotein IIb/IIa (Gp IIb/IIa)
Background: Human platelet membrane glycoprotein Glycoprotein IIb/IIIa (GP IIb/IIIa) is a dominate receptor on the platelet membrane with very high molecular weight (>200kDa). After the platelet is activated, the GP IIb/IIIa receptor complex changes conformation and binds to fibrinogen in blood circulation with high affinity. The activation of platelets is initiated locally when the endothelial layer is wounded and the platelets are exposed to the collagen underneath the endothelium. The fibrinogen aggregates with platelets when binding to the GP IIb/IIIa receptor on platelets, thus primary haemostasis (Platelet clot) is formed.