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mAb anti- Amyloid Beta Peptide 42
mAb anti- Amyloid Beta Peptide 42
- 中文名称：
- mAb anti- Amyloid Beta Peptide 42
- 英文名称：
- mAb anti- Amyloid Beta Peptide 42
- 品牌：
- AAA Biotech
- 品牌介绍：
- AAA Biotech专注于为全球生命科学研究提供高品质的蛋白质研究工具，核心产品包括经严格验证的抗体、重组蛋白及ELISA试剂盒。
- 货号：
- AAA77957
- 规格：
- 0.1 mg|0.5 mg|2x0.5 mg|3x0.5 mg|4x0.5 mg
- 保存建议：
- Store at -20°C
- 货期：
- 6-8周
- 来源宿主：
- Mouse
- 反应种属：
- Human and other primates; mouse and rat.
- 应用：
- IHC (Immunohistochemistry)
- 免责声明：
- *本产品仅供科研实验使用，不得用于临床诊断。*
- 其他：
克隆性:Monoclonal
同型:IgG2b,k
克隆号:[CA9 3F8]
特异性:This antibody recognizes the C-terminal sequence (MVGGVVIA) of Aß42 and full length Aß42.
纯度:Protein G Affinity Purified
形式：Lyophilized from a solution in 0.01M PBS pH7.2
浓度：N/A
- 说明书：
Description: Mouse monoclonal antibody to Cterminal of amyloid beta peptide 42 (Abeta42)
Background: Amyloid beta peptide 42 (Abeta42) is best known for its role in the formation of senile plaques in the brain of patients with Alzheimer's disease. Abeta42 and Abeta40 are the two major amyloid peptides that are produced after cleavage of amyloid precursor protein by secretases. Abeta42 (42 amino acids) is very fibrillogenic. The beta pleated structure of Abeta42 constituents the initial and key component of the insoluble amyloid fibril in senile plaque. It is widely accepted that Abeta42 contributes to the pathogenesis of Alzheimer's disease. One proposition is that the deposition of amyloid fibril onto the brain tissue results in Alzheimer's disease. Another is that the neurotoxicity of Abeta42 oligomer is the cause of the disease.
