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mAb anti-Human Programmed Cell Death-1
mAb anti-Human Programmed Cell Death-1
- 中文名称：
- mAb anti-Human Programmed Cell Death-1
- 英文名称：
- mAb anti-Human Programmed Cell Death-1
- 品牌：
- AAA Biotech
- 品牌介绍：
- AAA Biotech专注于为全球生命科学研究提供高品质的蛋白质研究工具，核心产品包括经严格验证的抗体、重组蛋白及ELISA试剂盒。
- 货号：
- AAA77960
- 规格：
- 0.1 mg|0.5 mg|2x0.5 mg|3x0.5 mg|4x0.5 mg
- 保存建议：
- 储存在-20摄氏度
- 货期：
- 6-8周
- 来源宿主：
- Mouse
- 反应种属：
- Human
- 应用：
- WB (Western Blot), ELISA (Indirect ELISA)
- 免责声明：
- *本产品仅供科研实验使用，不得用于临床诊断。*
- 其他：
克隆性:Monoclonal
同型:IgG1,k
克隆号:[1C4]
特异性:Reactive with recombinant human programmed cell death-1 (PD-1). Reactivity with natural PD-1 has not been evaluated.
纯度:Protein G Affinity Purified
形式：Lyophilized from a solution in 0.01M PBS, pH 7.2
浓度：N/A
- 说明书：
Description: Mouse monoclonal antibody (mAb) to human programmed cell death-1 (PD-1), or mouse mAb to human CD279.
Background: Programmed Cell Death-1 (PD-1), also called CD279, is a 288 amino acid cell surface protein that belongs to the immunoglobulin superfamily. The protein is expressed on T cells, B cells and macrophages. When PD-1 is joined with its ligand (CD274 or B7-H1), the immune cell's activation and effector function are attenuated. Research suggested that PD1 pathway is mainly involved with attenuation at periphery sites while the B7/CTLA-4 pathway is primarily involved with the attenuation of the activation of immune cells in secondary lymphoid organs. PD-1 pathway is implicated with cancer's immune-evasion, autoimmunity, and Listeria monocytogenes infection.
