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Mouse monoclonal antibody to human IL-17A, Clone 1E2
Mouse monoclonal antibody to human IL-17A, Clone 1E2
- 中文名称：
- Mouse monoclonal antibody to human IL-17A, Clone 1E2
- 英文名称：
- Mouse monoclonal antibody to human IL-17A, Clone 1E2
- 品牌：
- AAA Biotech
- 品牌介绍：
- AAA Biotech专注于为全球生命科学研究提供高品质的蛋白质研究工具，核心产品包括经严格验证的抗体、重组蛋白及ELISA试剂盒。
- 货号：
- AAA77965
- 规格：
- 0.1 mg|0.5 mg|2x0.5 mg|3x0.5 mg|4x0.5 mg
- 保存建议：
- Store at -20°C
- 货期：
- 6-8周
- 来源宿主：
- Mouse
- 反应种属：
- Human, others not tested
- 应用：
- WB (Western Blot), ELISA (Indirect ELISA)
- 免责声明：
- *本产品仅供科研实验使用，不得用于临床诊断。*
- 其他：
克隆性:Monoclonal
同型:IgG1, Kappa
克隆号:[1 E2]
特异性:Reactive with human IL-17A
纯度:Protein G affinity purified
形式：Lyophilized from a solution in 0.01M PBS, pH 7.0
浓度：N/A
- 说明书：
IL-17A is an inflammatory cytokine produced by Th17 cells, a newly characterised group of CD4 T help cells that plays a role in autoimmune diseases and chronic inflammatory diseases. IL-23 is the main inducer of Th17 cell development. Other cytokines such as TGF-beta, IL-6 and IL-21 were also found to contribute to the procedure. IL-17A belongs to the IL-17 family which includes IL-17A, IL-17B, IL-17C, IL-17D and IL-17E. IL-17, like interferon-gamma, is a potent mediator of delayed-type reaction. IL-17 induces the secretion of many other pro-inflammatory cytokines and chemokines such as IL-6, IL-8, GM-CSF, G-CSF, TGF-beta, TNF-alpha, GRO-alpha, and MCP-1. IL-17 stimulates the expression of NF-kappaB, mitogen activated protein kinase, and prostaglandings by many cell types, and enhances the production of nitric oxide.
