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anti-human CD278(ICOS)-APC
anti-human CD278(ICOS)-APC
- 中文名称：
- anti-human CD278(ICOS)-APC
- 英文名称：
- anti-human CD278(ICOS)-APC
- 品牌：
- AAA Biotech
- 品牌介绍：
- AAA Biotech专注于为全球生命科学研究提供高品质的蛋白质研究工具，核心产品包括经严格验证的抗体、重组蛋白及ELISA试剂盒。
- 货号：
- AAA78151
- 规格：
- 120 Tests|2x120 Tests|3x120 Tests|4x120 Tests|5x120 Tests
- 保存建议：
- Store at 2 - 5 degree C. Do not freeze! Protect from light.
- 货期：
- 6-8周
- 来源宿主：
- Mouse
- 反应种属：
- Human
- 免责声明：
- *本产品仅供科研实验使用，不得用于临床诊断。*
- 其他：
克隆性:Monoclonal
同型:IgG1k
克隆号:[ANC6C6]
特异性:N/A
纯度:N/A
形式：50 mM Sodium Phosphate pH 7.5, 500 mM Potassium Chloride, 150mM NaCl, 15% Glycerol, 0.2% BSA, 0.04% NaN3 (as a preservative).
浓度：N/A
- 说明书：
The inducible costimulator (ICOS, T cell activation molecule H4) is similar to human CD28 (24% homology), and plays an analogous role in the T cell activation process. Secondary signaling through CD28 or ICOS results in discrete cytokine secretion profiles by the activated T cells. Signaling by either molecule is effectively down regulated by CD152 (CTLA-4) engagement. Human GL50 is a member of the B7 family sharing ~20% homology with CD80 (B7-1) and CD86 (B7-2), and has been shown to be the ligand for ICOS. Two RNA splice variants exist for this molecule, differing only in the cytoplasmic domain. Antibody ANC6C6 binds to recombinant ICOS-muIg in EIA, and to the surface of HPB-MLT cells in Flow cytometry. Additionally, it blocks binding of recombinant GL50-muIg to HPB-MLT cells.
