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anti-human CD274(B7-H1)-R-PE
anti-human CD274(B7-H1)-R-PE
- 中文名称：
- anti-human CD274(B7-H1)-R-PE
- 英文名称：
- anti-human CD274(B7-H1)-R-PE
- 品牌：
- AAA Biotech
- 品牌介绍：
- AAA Biotech专注于为全球生命科学研究提供高品质的蛋白质研究工具，核心产品包括经严格验证的抗体、重组蛋白及ELISA试剂盒。
- 货号：
- AAA78173
- 规格：
- 120 Tests|2x120 Tests|3x120 Tests|4x120 Tests|5x120 Tests
- 保存建议：
- Store at 2 - 5°C. Do not freeze! Protect from light.
- 货期：
- 6-8周
- 来源宿主：
- Mouse
- 反应种属：
- Human
- 应用：
- ELISA, FCM/FACS (Flow Cytometry)
- 免责声明：
- *本产品仅供科研实验使用，不得用于临床诊断。*
- 其他：
克隆性:Monoclonal
同型:IgG1k
克隆号:[ANC6H1]
特异性:N/A
纯度:N/A
形式：50 mM Sodium Phosphate pH 7.5, 500 mM Potassium Chloride, 150mM NaCl, 15% Glycerol, 0.2% BSA, 0.04% NaN3 (as a preservative)
浓度：Volume: 0.2 ml
- 说明书：
Information: CD274 (B7-H1, PD-L1, Programmed Death Ligand) is a member of the B7 family and is expressed on a variety of tissues including lymphoid cells. It plays an important role in regulation of T cell activation, and is involved in progression of cancer, arthritis and HIV infection (3). CD274 binding to its receptor CD279 (PD-1) on activated T cells can decrease proliferation. Conversely, ligation of CD279 on primed T cells can stimulate IL-10 production. High levels of CD274 present in Renal cell carcinoma is associated with poor prognosis (1). Tumor expressed CD274 can increase apoptosis of tumor specific T cells resulting in better tumor cell survival (2). Gamma Interferon and PHA can up regulate CD274 expression on T cells. Antibody ANC6H1 binds to recombinant CD274 and native cell surface CD274 expressed on stimulated PBMC.
