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Monoclonal Antibody to mTLR3 (ABM24E5)
Monoclonal Antibody to mTLR3 (ABM24E5)
- 中文名称：
- Monoclonal Antibody to mTLR3 (ABM24E5)
- 英文名称：
- Monoclonal Antibody to mTLR3 (ABM24E5)
- 品牌：
- AAA Biotech
- 品牌介绍：
- AAA Biotech专注于为全球生命科学研究提供高品质的蛋白质研究工具，核心产品包括经严格验证的抗体、重组蛋白及ELISA试剂盒。
- 货号：
- AAA78212
- 规格：
- 0.025 mg|0.1 mg|2x0.1 mg|3x0.1 mg|4x0.1 mg
- 保存建议：
- Store the antibody at 4 degree C, stable for 6 months. For long-term storage, store at -20 degree C. Avoidrepeated freeze and thaw cycles.
- 货期：
- 6-8周
- 来源宿主：
- Rat
- 反应种属：
- Mouse, Human
- 应用：
- IHC (Immunohistochemistry), FCM/FACS (Flow Cytometry), WB (Western Blot)
- 免责声明：
- *本产品仅供科研实验使用，不得用于临床诊断。*
- 其他：
克隆性:Monoclonal
同型:Rat IgG2b, Kappa
克隆号:[ABM24E5]
特异性:N/A
纯度:Protein G Chromatography
形式：Purified (Liquid)
浓度：N/A
- 说明书：
Mouse Toll-like receptor 3 (mTLR3) belongs to a family of evolutionary conserved innate immune recognition molecules and recognizes double-stranded RNA, a molecular pattern associated with viral infections. It has seven exons. mTlr3 show high homology to hTLR3 in their predicted cDNA and protein sequences. The intracellular region of mTlr3 has remarkable homology with the same region of others mTlrs. mTlr3 mRNA is ubiquitously expressed in tissues, being expressed highest in spleen, kidney and lung. Its activation by the synthetic ligand polyinosine:polycytidylic acid (poly I:C) or by mRNA rapidly causes growth cone collapse and irreversibly inhibits neurite extension independent of NF-kappaB. The high levels of mTlr3 expression in Mz B cells perhaps contribute to their ability to clear antigen from the blood.
