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TLR5 Monoclonal Antibody
TLR5 Monoclonal Antibody
- 中文名称：
- TLR5 Monoclonal Antibody
- 英文名称：
- TLR5 Monoclonal Antibody
- 品牌：
- AAA Biotech
- 品牌介绍：
- AAA Biotech专注于为全球生命科学研究提供高品质的蛋白质研究工具，核心产品包括经严格验证的抗体、重组蛋白及ELISA试剂盒。
- 货号：
- AAA78243
- 规格：
- 0.025 mg|0.1 mg|2x0.1 mg|3x0.1 mg|4x0.1 mg
- 保存建议：
- Store the antibody at 4°C, stable for 6 months. For long-term storage, store at -20°C. Avoidrepeated freeze and thaw cycles
- 货期：
- 6-8周
- 来源宿主：
- N/A
- 反应种属：
- Human
- 应用：
- FCM/FACS (Flow Cytometry), IHC (Immunohistochemistry)
- 免责声明：
- *本产品仅供科研实验使用，不得用于临床诊断。*
- 其他：
克隆性:Monoclonal
同型:Mouse IgG2a Kappa
克隆号:[ABM22G1]
特异性:N/A
纯度:Protein G Chromatography
形式：Purified; 25 ug in 50 ul/100 ug in 200 ul PBS containing 0.05% BSA and 0.05% sodium azide. Sodium azide is highly toxic
浓度：N/A
- 说明书：
Toll-like receptor 5 (TLR5) plays a fundamental role in pathogen recognition and downstream signaling to induce effectiveimmunity. It is well expressed in major old tissues including lung, skin, intestine, and spleen. TLR5 is present in synovial ofpatients with rheumatoid arthritis (RA), act as novel mediator of innate immunity-induced osteoclastogenesis and bone loss.TLR5 is a receptor for flagellin and is present on the basolateral surface of intestinal epithelial cells. It is involved in the migrationof intestinal epithelial cells through activation of the p38 MAPK pathway. TLR5-mediated signaling specifically enhanced thematuration of lung dendritic cells. TLR5 influences the progression and outcome of ovarian, sarcoma, and luminal breasttumors. Mutations in TLR5 have been associated with both resistance and susceptibility to systemic lupus erythematosus, andsusceptibility to Legionnaire disease.
