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PDL-1
PDL-1
- 中文名称：
- PDL-1
- 英文名称：
- PDL-1
- 品牌：
- AAA Biotech
- 品牌介绍：
- AAA Biotech专注于为全球生命科学研究提供高品质的蛋白质研究工具，核心产品包括经严格验证的抗体、重组蛋白及ELISA试剂盒。
- 货号：
- AAA78250
- 规格：
- 0.025 mg|0.1 mg|2x0.1 mg|3x0.1 mg|4x0.1 mg
- 保存建议：
- Store the antibody at 4 degree C, stable for 6 months. For long-term storage, store at -20 degree C. Avoid repeated freeze and thaw cycles.
- 货期：
- 6-8周
- 来源宿主：
- Mouse
- 反应种属：
- Human
- 应用：
- WB (Western Blot), IHC (Immunohistochemistry), FCM/FACS (Flow Cytometry)
- 免责声明：
- *本产品仅供科研实验使用，不得用于临床诊断。*
- 其他：
克隆性:Monoclonal
同型:IgG2b, Kappa
克隆号:[ABM5F25]
特异性:N/A
纯度:Protein G Chromatography
形式：Purified; PBS containing 0.05% BSA and 0.05% sodium azide. Sodium azide is highly toxic
浓度：0.5 mg/ml
- 说明书：
PD-L 1 (CD274/B7-H1 ) is a critical membrane-bound costimulatory molecule belongs to the B7 superfamily that inhibits immune responses through its receptor, PD-1 and PD-L 1 playa key role in the pathogenesis of inflammatory diseases (programmed death 1). It is widely expressed in the mononuclear phagocy1e system (MPS), may co-stimulate T cells and regulates inflammatory responses. PD-L 1 exerts inflammation regulatory functions via a negative co-stimulatory effect on T cell functions to inhibit cytokine secretion , facilitate apoptosis of activated T cells and induce T cell anergy. Aberrant expression and dysregulation of CD274 have been reported during bacterial infection, inflammation and in numerous autoimmune diseases.
