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Monoclonal Antibody to CD10 (Clone: ABM4A52)
Monoclonal Antibody to CD10 (Clone: ABM4A52)
- 中文名称：
- Monoclonal Antibody to CD10 (Clone: ABM4A52)
- 英文名称：
- Monoclonal Antibody to CD10 (Clone: ABM4A52)
- 品牌：
- AAA Biotech
- 品牌介绍：
- AAA Biotech专注于为全球生命科学研究提供高品质的蛋白质研究工具，核心产品包括经严格验证的抗体、重组蛋白及ELISA试剂盒。
- 货号：
- AAA78260
- 规格：
- 0.025 mg|0.1 mg|2x0.1 mg|3x0.1 mg|4x0.1 mg
- 保存建议：
- Store the antibody at 4 degree C, stable for 6 months.
For long-term storage, store at -20 degree C.
Avoid repeated freeze and thaw cycles.
- 货期：
- 6-8周
- 来源宿主：
- Mouse
- 反应种属：
- Human
- 应用：
- WB (Western Blot), IHC (Immunohistochemistry)
- 免责声明：
- *本产品仅供科研实验使用，不得用于临床诊断。*
- 其他：
克隆性:Monoclonal
同型:IgG2b Kappa
克隆号:[ABM4A52]
特异性:N/A
纯度:Purified
Protein G Chromatography
形式：25 ug in 50 ul/100 ug in 200 ul PBS containing 0.05% BSA and 0.05% sodium azide. Sodium azide is highly toxic.
浓度：N/A
- 说明书：
CD10, also known as membrane metalloendopeptidase, neutral endopeptidase, neprilysin and common acute lymphoblastic leukaemia antigen (CALLA), is a zinc-dependent metalloendoprotease that cleaves signaling peptides. It is widely expressed in various normal tissues and in epithelial, stromal or both components of various malignancies. CD10 is a marker for intestinal epithelial brush border. It is also present in normal bile ducts and gallbladder epithelia but is absent in cholangiocarcinomas. It is con-sidered as the prototype of this family of membrane-bound, zinc-dependent endopeptidases, which regulate the physiological action of various peptides by lowering their extracellular concentration available for receptor binding. CD10 is also known to be an amyloid b-peptide (Ab) degrading enzyme. Polymorphisms in the CD10 gene increase the risk for Alzheimer's disease. Outside the nervous system, it is present on the surface of neutrophils and regulates their activation by degradation of inflammatory peptides.
