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Monoclonal Antibody to TLR4 (Clone: HTA125)
Monoclonal Antibody to TLR4 (Clone: HTA125)
- 中文名称：
- Monoclonal Antibody to TLR4 (Clone: HTA125)
- 英文名称：
- Monoclonal Antibody to TLR4 (Clone: HTA125)
- 品牌：
- AAA Biotech
- 品牌介绍：
- AAA Biotech专注于为全球生命科学研究提供高品质的蛋白质研究工具，核心产品包括经严格验证的抗体、重组蛋白及ELISA试剂盒。
- 货号：
- AAA78288
- 规格：
- 25 Tests|100 Tests|2x100 Tests|3x100 Tests|4x100 Tests
- 保存建议：
- Store the antibody at 4 degree C, stable for 6 months.
- 货期：
- 6-8周
- 来源宿主：
- Mouse
- 反应种属：
- Human
- 应用：
- FCM/FACS (Flow Cytometry)
- 免责声明：
- *本产品仅供科研实验使用，不得用于临床诊断。*
- 其他：
克隆性:Monoclonal
同型:IgG2a
克隆号:[HTA125]
特异性:N/A
纯度:Protein G Chromatography
形式：0.2 mg/ml in PBS with 0.05% Azide.
浓度：N/A
- 说明书：
TLR4 (Toll-like receptor-4) is a member of the Toll-like receptor (TLR) family which plays a fundamental role in pathogen recognition and activation of innate immunity. It primarily mediates cellular signaling induced by Gram-negative bacteria. TLR4 is highly specific for LPS and it is associated with CD14, a co-receptor for LPS. The downstream signaling pathway of TLR4 leads to the activation of NF-kappaB through myeloid differentiation protein (MyD88) and IL-1 receptor-associated kinase in various cell types. Keratinocytes express TLR4 at the mRNA and protein levels whereas TLR4 are also present in the normal human epidermis in vivo and their expression is regulated by microbial components. TLR4 is expressed on CD4+ T cells as well, the functional significance of which is unclear.
