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Polyclonal Antibody to BAG5
Polyclonal Antibody to BAG5
- 中文名称:
- Polyclonal Antibody to BAG5
- 英文名称:
- Polyclonal Antibody to BAG5
- 品牌:
- AAA Biotech
- 品牌介绍:
- AAA Biotech专注于为全球生命科学研究提供高品质的蛋白质研究工具,核心产品包括经严格验证的抗体、重组蛋白及ELISA试剂盒。
- 货号:
- AAA78304
- 规格:
- 0.05 mL|2x0.05 mL|3x0.05 mL|4x0.05 mL|5x0.05 mL
- 保存建议:
- Store the antibody at 4 degree C, stable for 6 months.
For long-term storage, store at -20 degree C.
Avoid repeated freeze and thaw cycles.
- 货期:
- 6-8周
- 来源宿主:
- Rabbit
- 反应种属:
- Cow, Dog, Human, Mouse, Rat
- 应用:
- ICC (Immunocytochemistry), IF (Immunofluorescence), IP (Immunoprecipitation), IHC (Immunohistochemistry), WB (Western Blot)
- 免责声明:
- *本产品仅供科研实验使用,不得用于临床诊断。*
- 其他:
克隆性:Polyclonal
同型:IgG
克隆号:N/A
特异性:N/A
纯度:Serum
形式:50 ul sera
浓度:N/A
- 说明书:
The BAG proteins are a family of chaperone regulators that modulate a number of diverse processes including proliferation, survival, stress responses, tumorigenesis, neuronal differentiation, growth arrest and. BAG proteins have been characterized as co-chaperones and interact with the chaperone heat shock proteins 70, both constitutive Hsc70 and inducible Hsp70. BAG proteins bind through their BAG domain to the ATPase domain of Hsc70/Hsp70, and can modulate either positively or negatively the functions of the Hsc70/Hsp70 chaperone proteins. The BAG domain has been shown to contribute to the anti-apoptotic activity of BAG- family proteins. The anti-apoptotic activities of BAG-family proteins may be dependent on their interactions with Hsc70/Asp70 and/or binding to Bcl-2. In addition to the conserved BAG domain, BAG-family proteins also contain additional domains which enable them to interact with specific target proteins or to target them to specific locations within cells. The BAG family contains at least six family members, including BAG-1 and its various isoforms [including BAG-1S, BAG-1M (RAP46/HAP46), and BAG-1L, BAG2, BAG3 (CAIR-1; Bis, ), BAG4 (SODD), BAG5 and BAG6 (Scythe, BAT3).