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Monoclonal Antibody to TLR6 (Clone: ABM1B50)-FITC Conjugated
Monoclonal Antibody to TLR6 (Clone: ABM1B50)-FITC Conjugated
- 中文名称：
- Monoclonal Antibody to TLR6 (Clone: ABM1B50)-FITC Conjugated
- 英文名称：
- Monoclonal Antibody to TLR6 (Clone: ABM1B50)-FITC Conjugated
- 品牌：
- AAA Biotech
- 品牌介绍：
- AAA Biotech专注于为全球生命科学研究提供高品质的蛋白质研究工具，核心产品包括经严格验证的抗体、重组蛋白及ELISA试剂盒。
- 货号：
- AAA78405
- 规格：
- 0.1 mg|2x0.1 mg|3x0.1 mg|4x0.1 mg|5x0.1 mg
- 保存建议：
- Store the antibody at 4 degree C, stable for 6 months.
- 货期：
- 6-8周
- 来源宿主：
- Mouse
- 反应种属：
- Human
- 应用：
- FCM/FACS (Flow Cytometry)
- 免责声明：
- *本产品仅供科研实验使用，不得用于临床诊断。*
- 其他：
克隆性:Monoclonal
同型:IgG1 Kappa
克隆号:[ABM1B50]
特异性:N/A
纯度:Purified
Protein G Chromatography
形式：0.2 mg/ml in Tris buffer containing 0.05% Azide
浓度：N/A
- 说明书：
TLR6 (Toll-Like Receptors 6) is a member of the TLR (Toll-like receptor) family that plays a fundamental role in pathogen recognition and activation of innate immunity. TLR6 forms heterodimers with TLR1 and TLR2, which is the initial step in a cascade of events leading to significant innate immune responses, development of adaptive immunity to pathogens and protection from immune sequelae related to infection with these pathogens. TLR2 in co-operation with TLR6 trigger inflammatory responses via activation of NF-kappaB, which regulates the transcription of inflammatory molecules. TLR6 has emerged as the most potent activator for ZNPs (Zinc Oxide Nanoparticles)-induced inflammatory responses. Upon silencing, TLR6 significantly inhibited the pro-inflammatory cytokine levels, reactive nitrogen species generation and inducible nitric oxide synthase expression.
