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Monoclonal Antibody to hPD-L1 (Clone: ABM4E54) PE Conjugated
Monoclonal Antibody to hPD-L1 (Clone: ABM4E54) PE Conjugated
- 中文名称：
- Monoclonal Antibody to hPD-L1 (Clone: ABM4E54) PE Conjugated
- 英文名称：
- Monoclonal Antibody to hPD-L1 (Clone: ABM4E54) PE Conjugated
- 品牌：
- AAA Biotech
- 品牌介绍：
- AAA Biotech专注于为全球生命科学研究提供高品质的蛋白质研究工具，核心产品包括经严格验证的抗体、重组蛋白及ELISA试剂盒。
- 货号：
- AAA78431
- 规格：
- 100 Tests|2x100 Tests|3x100 Tests|4x100 Tests|5x100 Tests
- 保存建议：
- Store the antibody at 4°C; stable for 6 months.
- 货期：
- 6-8周
- 来源宿主：
- Mouse
- 反应种属：
- Human
- 应用：
- FCM/FACS (Flow Cytometry)
- 免责声明：
- *本产品仅供科研实验使用，不得用于临床诊断。*
- 其他：
克隆性:Monoclonal
同型:IgG2a Kappa
克隆号:[ABM4E54]
特异性:N/A
纯度:Protein G Chromatography
形式：Purified
25 Test in 125 ul/100 Test in 500 ?l PBS containing 0.05% sodium azide. Sodium azide is highly toxic.
浓度：N/A
- 说明书：
PD-L1 (CD274/B7-H1) is a critical membrane-bound costimulatory molecule belongs to the B7 superfamily that inhibits immune responses through its receptor, PD-1 and PD-L1 play a key role in the pathogenesis of inflammatory diseases (programmed death 1). It is widely expressed in the mononuclear phagocyte system (MPS), may co-stimulate T cells and regulates inflammatory responses. PD-L1 exerts inflammation regulatory functions via a negative co-stimulatory effect on T cell functions to inhibit cytokine secretion, facilitate apoptosis of activated T cells and induce T cell anergy. Aberrant expression and dysregulation of CD274 have been reported during bacterial infection, inflammation and in numerous autoimmune diseases.
