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Mouse Anti-Human IL-31-BIOT
Mouse Anti-Human IL-31-BIOT
- 中文名称:
- Mouse Anti-Human IL-31-BIOT
- 英文名称:
- Mouse Anti-Human IL-31-BIOT
- 品牌:
- AAA Biotech
- 品牌介绍:
- AAA Biotech专注于为全球生命科学研究提供高品质的蛋白质研究工具,核心产品包括经严格验证的抗体、重组蛋白及ELISA试剂盒。
- 货号:
- AAA78625
- 规格:
- 0.1 mg|2x0.1 mg|3x0.1 mg|4x0.1 mg|5x0.1 mg
- 保存建议:
- The biotin (BIOT) conjugate is supplied as 0.5mg labeled antibody in 0.2mL of PBS/NaN3. Store at 2-8 degree C.
- 货期:
- 6-8周
- 来源宿主:
- Mouse
- 反应种属:
- Human
- 应用:
- ELISA
- 免责声明:
- *本产品仅供科研实验使用,不得用于临床诊断。*
- 其他:
克隆性:Monoclonal
同型:IgG2b
克隆号:[SB118b1]
特异性:Reacts with native and recombinant human IL-311
纯度:N/A
形式:Biotin (BIOT) Conjugate
浓度:N/A
- 说明书:
Description: Interleukin-31 (IL-31) is a 24kD alpha-helical protein and a member of the IL-6 family of cytokines that is preferentially expressed by CD4+ T cells (2). This cytokine elicits its response by binding to a heterodimeric complex consisting of a gp130-like receptor chain and the oncostatin M receptor subunit. On target cells which include a broad range of immune and non-immune cells, IL-31 binding can induce activation of the Jak/STAT, AKT and MAPK signaling pathways. Due to the ubiquitous expression of its receptor complex, IL-31 has numerous physiological roles that include regulating hematopoiesis and immune response (3,4). Over-expression has been linked chronic inflammatory states such as dermatitis, pruritus, airway hypersensitivity and inflammatory bowel disease5-7.