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Mouse Anti-Human CD49d/VLA-4-FITC
Mouse Anti-Human CD49d/VLA-4-FITC
- 中文名称:
- Mouse Anti-Human CD49d/VLA-4-FITC
- 英文名称:
- Mouse Anti-Human CD49d/VLA-4-FITC
- 品牌:
- AAA Biotech
- 品牌介绍:
- AAA Biotech专注于为全球生命科学研究提供高品质的蛋白质研究工具,核心产品包括经严格验证的抗体、重组蛋白及ELISA试剂盒。
- 货号:
- AAA78631
- 规格:
- 100 Tests|2x100 Tests|3x100 Tests|4x100 Tests|5x100 Tests
- 保存建议:
- The fluorescein (FITC) conjugate is supplied as 100 tests in 1.0 mL of PBS/NaN3. Store at 2-8 degree C
- 货期:
- 6-8周
- 来源宿主:
- Mouse
- 反应种属:
- Human
- 免责声明:
- *本产品仅供科研实验使用,不得用于临床诊断。*
- 其他:
克隆性:N/A
同型:IgG1 kappa
克隆号:[7.2]
特异性:Human CD49d; Mr 150kDa
纯度:N/A
形式:Fluorescein (FITC) Conjugate
浓度:N/A
- 说明书:
CD49d, a member of the integrin family of extracellular matrix and cell adhesion molecules, is the integrin ?4 chain. CD49d associates noncovalently with CD29, the integrin ?1 subunit, to form the ?4?1 very late antigen-4 (VLA-4) heterodimer. Integrin ?4 can also associate with integrin ?7 to form the ?4?7 heterodimer. It is expressed on most leukocytes with the possible exception of neutrophils. VLA-4 mediates leukocyte binding to CD106 (VCAM-1) and is involved in the migration of leukocytes from blood to tissue at sites of inflammation. VLA-4 can also provide a costimulatory signal to T cells for activation and proliferation. The ?4?7 integrin heterodimer is expressed on a small subpopulation of thymocytes, most lymph node T and B lymphocytes, NK cells, and eosinophils. Integrin ?4?7 also binds to fibronectin and VCAM-1