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Rat Anti-Mouse CD44/Pgp-1-UNLB
Rat Anti-Mouse CD44/Pgp-1-UNLB
- 中文名称：
- Rat Anti-Mouse CD44/Pgp-1-UNLB
- 英文名称：
- Rat Anti-Mouse CD44/Pgp-1-UNLB
- 品牌：
- AAA Biotech
- 品牌介绍：
- AAA Biotech专注于为全球生命科学研究提供高品质的蛋白质研究工具，核心产品包括经严格验证的抗体、重组蛋白及ELISA试剂盒。
- 货号：
- AAA78661
- 规格：
- 0.5 mg|2x0.5 mg|3x0.5 mg|4x0.5 mg|5x0.5 mg
- 保存建议：
- Store at 2-8°C.
- 货期：
- 6-8周
- 来源宿主：
- N/A
- 反应种属：
- N/A
- 应用：
- FCM/FACS (Flow Cytometry)
- 免责声明：
- *本产品仅供科研实验使用，不得用于临床诊断。*
- 其他：
克隆性:N/A
同型:Rat (LOU/MN) IgG1 k
克隆号:[KM201]
特异性:Mouse CD44 (all isoforms); Mr 80-95 kDa
纯度:N/A
形式：Supplied as 0.5 mg of purified immunoglobulin in 1.0 mL of borate buffered saline, pH 8.2.
浓度：N/A
- 说明书：
CD44 represents a family of type I transmembrane glycoproteins expressed on many cell types such as B cells, monocytes, macrophages, and variable subsets of thymocytes and peripheral T cells. CD44 primarily functions as an adhesion molecule. It has been implicated in various processes, such as hematopoiesis, lymphocyte homing, leukocyte activation, tumor metastasis and development. The KM201 monoclonal antibody reacts with an epitope very close to the hyaluronate binding domain on the CD44 molecule. KM201 can inhibit hyaluronate-dependent cell aggregation, prevent lympho-hemopoiesis in both Dexter and Whitlock-Witte cultures, prevent the earliest intrathymic precursors from homing to the thymus, and costimulate the activation of freshly purified splenic CD4+ T cells.
