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Rat Anti-Mouse CD11b/Mac-1a-UNLB
Rat Anti-Mouse CD11b/Mac-1a-UNLB
- 中文名称：
- Rat Anti-Mouse CD11b/Mac-1a-UNLB
- 英文名称：
- Rat Anti-Mouse CD11b/Mac-1a-UNLB
- 品牌：
- AAA Biotech
- 品牌介绍：
- AAA Biotech专注于为全球生命科学研究提供高品质的蛋白质研究工具，核心产品包括经严格验证的抗体、重组蛋白及ELISA试剂盒。
- 货号：
- AAA78669
- 规格：
- 0.5 mg|2x0.5 mg|3x0.5 mg|4x0.5 mg|5x0.5 mg
- 保存建议：
- Store at 2- 8°C.
The purified (UNLB) antibody is supplied as 0.5 mg of purified immunoglobulin in 1.0 mL of borate buffered saline, pH 8.2. No preservatives or amine-containing buffer salts added.
- 货期：
- 6-8周
- 来源宿主：
- Rat
- 反应种属：
- Mouse
- 应用：
- FCM/FACS (Flow Cytometry)
- 免责声明：
- *本产品仅供科研实验使用，不得用于临床诊断。*
- 其他：
克隆性:Monoclonal
同型:Rat (Dark Agouti) IgG2bkappa
克隆号:[M1/70]
特异性:Mouse/Human/Rhesus/Baboon/Rabbit CD11b; Mr 170 kDa
纯度:N/A
形式：Purified (UNLB) Antibody
浓度：N/A
- 说明书：
CD11b, the integrin alphaM subunit, combines with CD18, the integrin B2 subunit, to form the integrin Mac-1, also known as complement receptor 3 (CR3), which mediates adhesion to C3bi and ICAM-1/CD54. Mac-1 is expressed at varying levels on granulocytes, macrophages, dendritic cells, NK cells, and B-1 cells in the peritoneal and pleural cavities. Mac-1 expression is rapidly up-regulated on neutrophils after activation and in the same time period that CD62L is shed from the cell surface. In addition to its role in binding C3bi on opsonized targets and mediation of the subsequent ingestion process, Mac-1 is important as an adhesion molecule in the transendothelial migration of monocytes and neutrophils. Cross-reaction of M1/70 to human CD11b has been observed on monocytes, polymorphonuclear leukocytes, and NK cells.
