Rat Anti-Mouse CD54/ICAM-1-BIOT-Rat Anti-Mouse CD54/ICAM-1-BIOT-一抗检测抗体

: Rat Anti-Mouse CD54/ICAM-1-BIOT

Rat Anti-Mouse CD54/ICAM-1-BIOT

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应用：: WB (Western Blot), IP (Immunoprecipitation), IHC (Immunohistochemistry), FCM/FACS (Flow Cytometry)

其他：: 克隆性:Monoclonal
同型:IgG_{2b κ}
克隆号:[YN1/1.7.4]
特异性:Mouse CD54/ICAM-1, Mr 95 kDa
CD54, a member of the immunoglobulin superfamily of cell surface receptors and also known as Intercellular Adhesion Molecule-1 (ICAM-1), is a type I transmembrane glycoprotein that mediates important cell/cell interactions. CD54 is expressed on endothelial cells, dendritic cells, keratinocytes and lymphocytes. Its expression is upregulated by inflammatory mediators such as IFN- gamma, IL-1, TNF- alpha, lipopolysaccharide and phorbol esters. Endothelial CD54 contributes to the extravasation of leukocytes from blood vessels, particularly in areas of inflammation. CD54 on antigen-presenting cells contributes to antigen-specific T-cell activation, presumably by enhancing interactions between T cell and antigen-presenting cells. These adhesion reactions are mediated via the binding of CD54 to its major ligands, LFA-1 and Mac-1.
纯度:N/A
形式：The biotin (BIOT) conjugate is supplied as 0.5 mg in 1.0 mL of PBS/NaN3.
浓度：N/A