
Rat Anti-Mouse CD107a/LAMP-1-UNLB
克隆性:Monoclonal
同型:Rat (Sprague-Dawley) IgG2a kappa
克隆号:[1D4B]
特异性:Murine CD107a/LAMP-1 (Mr 110-140 kDa with a core protein of Mr ~40 kDa)
CD107a, also known as lysosomal-associated membrane protein 1 (LAMP-1), is a heavily glycosylated, type I transmembrane protein that constitutes one of the two major sialoglycoproteins on lysosomal membranes that can be used to distinguish lysosomes from other organelles.^1 It is a ligand for galaptin, an S-type lectin present in extracellular matrix, through its recognition of acetyllactosamine oligosaccharide chains, and is a ligand for E-selectin-mediated cell adhesion.^2 CD107a is principally expressed in epithelial cells and macrophages in a variety of organs in normal and Beige mutant mice.^3 LAMP-1 may function in protecting the inner surface of the lysosomal membrane by forming a barrier to lysosomal hydrolases.^4
纯度:N/A
形式:Purified (UNLB) Antibody
浓度:N/A

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