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Mouse Anti-Chicken TCRgd-BIOT
Mouse Anti-Chicken TCRgd-BIOT
- 中文名称：
- Mouse Anti-Chicken TCRgd-BIOT
- 英文名称：
- Mouse Anti-Chicken TCRgd-BIOT
- 品牌：
- AAA Biotech
- 品牌介绍：
- AAA Biotech专注于为全球生命科学研究提供高品质的蛋白质研究工具，核心产品包括经严格验证的抗体、重组蛋白及ELISA试剂盒。
- 货号：
- AAA78703
- 规格：
- 0.5 mg|2x0.5 mg|3x0.5 mg|4x0.5 mg|5x0.5 mg
- 保存建议：
- The biotin (BIOT) conjugate is supplied as 0.5 mg in 1.0 mL of PBS/NaN3. Store at 2-8 degree C.
- 货期：
- 6-8周
- 来源宿主：
- Mouse
- 反应种属：
- Chicken
- 应用：
- IP (Immunoprecipitation), IHC (Immunohistochemistry), FCM/FACS (Flow Cytometry)
- 免责声明：
- *本产品仅供科研实验使用，不得用于临床诊断。*
- 其他：
克隆性:Monoclonal
同型:Mouse (BALB/c) IgG1K
克隆号:[TCR1]
特异性:Chicken/Milk Snake TCR gamma/delta; Mr 50 & 40 kDa
纯度:N/A
形式：Biotin (BIOT) Conjugate
浓度：N/A
- 说明书：
The monoclonal antibody TCR-1 precipitates a heterodimer of Mr 90 kDa (two bands of Mr 50 kDa and 40 kDa upon reduction) on chicken peripheral blood T cells. Deglycosylation of the heterodimer yields two polypeptides of Mr 35 kDa and 32 kDa. Unlike human and mouse in which yo cells comprise a minor subset of T lymphocytes in the circulation, the chicken has a relatively large subset of yo T cells. The frequency of TCRgamma/delta cells is typically 20-25% of the total blood T cells but may reach approximately 50% in chickens of six- months of age. The majority of TCRgamma/delta+ cells in the thymus and blood are CD4-CD8- although a small subset of them may express CD8 or CD4 coreceptors. However, when the TCRgamma/delta+ cells migrate into the spleen and intestine most of them begin to express CD8. Although the biological function of yo T cells is unclear, they are clearly capable of cytotoxic activity in vitro. The CD8+ yo T cells may also be involved in down-regulation of the immune response. They cannot, however, induce a graft-vs-host (GVH) reactions.
