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Mouse Anti-Human PlGF-2
Mouse Anti-Human PlGF-2
- 中文名称：
- Mouse Anti-Human PlGF-2
- 英文名称：
- Mouse Anti-Human PlGF-2
- 品牌：
- AAA Biotech
- 品牌介绍：
- AAA Biotech专注于为全球生命科学研究提供高品质的蛋白质研究工具，核心产品包括经严格验证的抗体、重组蛋白及ELISA试剂盒。
- 货号：
- AAA79330
- 规格：
- 0.1 mg|2x0.1 mg|3x0.1 mg|4x0.1 mg|5x0.1 mg
- 保存建议：
| Product Form | Temperature | Storage Time |
|---|
| Lyophilized | -20°C to -80°C | Long Term |
| Lyophilized | 4°C | 3 Months |
| Lyophilized | Room Temperature | 1 Month |
| Reconstituted | 2°C to 8°C | 2 Weeks |
| Extended Storage | -20°C to -80°C | 6 Months |
Extended Storage
After initial reconstitution, the addition of a carrier protein or 50% glycerol is recommended for extended storage. Prepare and store working aliquots at -20°C to -80°C.
- 货期：
- 6-8周
- 来源宿主：
- Mouse
- 反应种属：
- No cross reactivity with mouse and rat PIGF.
- 应用：
- IF (Immunofluorescence), WB (Western Blot), ELISA
- 免责声明：
- *本产品仅供科研实验使用，不得用于临床诊断。*
- 其他：
克隆性:Monoclonal
同型:IgG1
克隆号:[3B3/A9/A6/D1]
特异性:N/A
纯度:Protein G purified
形式：Sterile filtered antibody solution was lyophilized from PBS; does not contain stabilizers or preservatives.
浓度：N/A
- 说明书：
Human Placenta Growth Factor-2 (PlGF-2), a 22 kDa protein consisting of 152 amino acid residues is produced as a homodimer. PlGF is a polypeptide growth factor and a member of the platelet-derived growth factor family but more related to vascular endothelial growth factor (VEGF). PlGF acts only as a weak mitogen for those cell types possessing receptors for binding (e.g. vascular endothelial cells). At least one high-affinity receptor for PlGF (FLT-1 or VEGF-R1) has been demonstrated in different primary cell types (e.g. human umbilical vein endothelial cells and monocytes). In addition to its action as a weak mitogen it is also a chemoattractant for monocytes and endothelial cells. Three different proteins are generated by differential splicing of the human PlGF gene: PlGF-1 (131aa native chain), PlGF-2 (152aa) and PlGF-3 (203aa). All 3 mitogens are secretable proteins, but PlGF-2 can bind to heparin with high affinity. PlGF is apparently a homodimer, but preparations of PlGF show some heterogeneity on SDS gels depending of the varying degrees of glycosylation. All dimeric forms possess similar biological activities. Heterodimers between VEGF and PlGF are mitogenic for endothelial cells and have strong angiogenic activity in vivo (e.g. in the CAM assay or in the cornea pocket assay). Different cells and tissues (e.g. placenta) express PlGF-1 and PlGF-2 at different rates. A much related protein of PlGF is VEGF with about 53% homology and VEGF-B with similar biological activities.
