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Rabbit anti-human kininogen 1 polyclonal Antibody
Rabbit anti-human kininogen 1 polyclonal Antibody
- 中文名称:
- Rabbit anti-human kininogen 1 polyclonal Antibody
- 英文名称:
- Rabbit anti-human kininogen 1 polyclonal Antibody
- 品牌:
- AAA Biotech
- 品牌介绍:
- AAA Biotech专注于为全球生命科学研究提供高品质的蛋白质研究工具,核心产品包括经严格验证的抗体、重组蛋白及ELISA试剂盒。
- 货号:
- AAA81092
- 规格:
- 0.1 mL|2x0.1 mL|3x0.1 mL|4x0.1 mL|5x0.1 mL
- 保存建议:
- 请按照说明书指示
- 货期:
- 6-8周
- 来源宿主:
- Rabbit
- 反应种属:
- Human; Other species are not tested. Please decide the specificity by homology.
- 应用:
- IHC (Immunohistochemistry), WB (Western Blot), ELISA
- 免责声明:
- *本产品仅供科研实验使用,不得用于临床诊断。*
- 其他:
克隆性:Polyclonal
同型:IgG
克隆号:N/A
特异性:N/A
纯度:Antigen Affinity Purified
形式:Liquid
浓度:N/A
- 说明书:
(1)Kininogens are inhibitors of thiol proteases; (2) HMW-kininogen plays an important role in blood coagulation by helping to position optimally prekallikreinand factor XI next to factor XII; (3) HMW-kininogen inhibits the thrombin-and plasmin-induced aggregation of thrombocytes; (4) the active peptide bradykinin that is released from HMW-kininogen shows a variety of physiological effects: (4A) influence in smooth muscle contraction, (4B) induction of hypotension, (4C) natriuresis and diuresis, (4D) decrease in blood glucose level, (4E) it is a mediator of inflammation and causes (4E1) increase in vascular permeability, (4E2) stimulation of nociceptors (4E3) release of other mediators of inflammation (e.g. prostaglandins), (4F) it has a cardioprotective effect (directly via bradykinin action, indirectly via endothelium-derived relaxing factor action); (5) LMW-kininogen inhibits the aggregation of thrombocytes; (6) LMW-kininogen is in contrast to HMW-kininogen not involved in blood clotting.