
-
CBL0137
CBL0137
- 中文名称:
- CBL0137
- 英文名称:
- CBL0137
- 品牌:
- AAA Biotech
- 品牌介绍:
- AAA Biotech专注于为全球生命科学研究提供高品质的蛋白质研究工具,核心产品包括经严格验证的抗体、重组蛋白及ELISA试剂盒。
- 货号:
- AAA201893
- 规格:
- 5 mg|10 mg|25 mg|50 mg|100 mg
- 保存建议:
- Store at -20°C
Stability: >2 years
- 货期:
- 6-8周
- 纯度:
- >98% (HPLC)
- 产品形式:
- N/A
- 免责声明:
- *本产品仅供科研实验使用,不得用于临床诊断。*
- 说明书:
MBS3600708 (Curaxin) is a histone chaperone FACT (facilitates chromatin transcription) and MYC signal inhibitor that markedly reduced tumor initiation and progression in vivo; simultaneously activates p53 and inhibits NF-kappaB without causing detectable genotoxicity, causes phosphorylation of p53 Ser (392) by CK2 and inhibition of NF-kappaB-dependent transcription in neuroblastoma cells; eradicates drug resistant cancer stem cells and potentiates efficacy of gemcitabine in preclinical models of pancreatic cancer. Brain Cancer Phase 1 Clinical