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Tofogliflozin hydrate
Tofogliflozin hydrate
- 中文名称:
- Tofogliflozin hydrate
- 英文名称:
- Tofogliflozin hydrate
- 品牌:
- AAA Biotech
- 品牌介绍:
- AAA Biotech专注于为全球生命科学研究提供高品质的蛋白质研究工具,核心产品包括经严格验证的抗体、重组蛋白及ELISA试剂盒。
- 货号:
- AAA201894
- 规格:
- 2 mg|5 mg|10 mg|25 mg|50 mg
- 保存建议:
- Store at -20 degree C
Stability: >2 years
- 货期:
- 6-8周
- 纯度:
- >98% (HPLC)
- 产品形式:
- N/A
- 免责声明:
- *本产品仅供科研实验使用,不得用于临床诊断。*
- 说明书:
Tofogliflozin (CSG-452) is a potent, highly selective SGLT2 inhibitor with Ki of 2.9, 14.9, and 6.4nM against human, rat, and mouse SGLT2, respectively; displays high selectivity over human SGLT2 versus human SGLT1, SGLT6, and sodium/myo-inositol transporter 1; increases renal glucose clearance and lowered the blood glucose level in Zucker diabetic fatty rats, also improves postprandial glucose excursion; reduces glycated hemoglobin and improved glucose tolerance in the oral glucose tolerance test in vivo. Diabetes Approved