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Recombinant Human Galectin-3
Recombinant Human Galectin-3
- 中文名称：
- Recombinant Human Galectin-3
- 英文名称：
- Recombinant Human Galectin-3
- 品牌：
- AAA Biotech
- 品牌介绍：
- AAA Biotech专注于为全球生命科学研究提供高品质的蛋白质研究工具，核心产品包括经严格验证的抗体、重组蛋白及ELISA试剂盒。
- 货号：
- AAA38591
- 规格：
- 0.01 mg|0.05 mg|1 mg|2x1 mg|3x1 mg
- 保存建议：
- Lyophilized Galectin-3 Recombinant although stable at room temperature for 3 weeks, should be stored desiccated below -18 degree C. Upon reconstitution Galectin-3 should be stored at 4 degree C between 2-7 days and for future use below -18 degree C.For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).Please prevent freeze-thaw cycles.
- 货期：
- 6-8周
- 纯度：
- Greater than 97.0% as determined by analysis by SDS-PAGE and HPLC.
- 产品形式：
- The Galectin-3 protein was lyophilized from a 0.2 um filtered concentrated solution in PBS, pH 7.4 and 3mM DTT.
Sterile Filtered White lyophilized (freeze-dried) powder.
- 免责声明：
- *本产品仅供科研实验使用，不得用于临床诊断。*
- 说明书：
Description: LGALS3 Human Recombinant produced in E Coli is a single, non-glycosylated, polypeptide chain containing 249 amino acids and having a molecular mass of 26kDa.The LGALS3 is purified by proprietary chromatographic techniques.
Introduction: Galectin-3 mediates with the alpha-3, beta-1 integrin the stimulation by cspg4 of endothelial cells migration. Galectin-3 plays an necessary part during the acquisition of vasculogenic mimicry and angiogenic properties associated with melanoma progression. LGALS3 overexpression is highly expressed in early stages of papillary carcinoma, and its expression intensity declines during tumor progression. Serum levels of LGALS3 are high in patients with thyroid malignancy but there is considerable overlap in serum LGALS3 concentrations between those with benign and malignant nodular thyroid disease. LGLAS3 takes part as an immune regulator to inhibit T-cell immune responses and promote tumor growth, as a result providing a new mechanism for tumor immune tolerance.
