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Human NNT-1/BCSF-3
Human NNT-1/BCSF-3
- 中文名称:
- Human NNT-1/BCSF-3
- 英文名称:
- Human NNT-1/BCSF-3
- 品牌:
- AAA Biotech
- 品牌介绍:
- AAA Biotech专注于为全球生命科学研究提供高品质的蛋白质研究工具,核心产品包括经严格验证的抗体、重组蛋白及ELISA试剂盒。
- 货号:
- AAA79298
- 规格:
- 0.002 mg|0.01 mg|2x0.01 mg|3x0.01 mg|4x0.01 mg
- 保存建议:
- The lyophilized protein is stable at room tempeture for 1 month and at 4°C for 6 months. Reconstituted working aliquots are stable for 1 week at 2°C to 8°C and for 3 months at -20°C to -80°C. Avoid repeated freeze thaw cycles.
- 货期:
- 6-8周
- 纯度:
- > 98% by SDS-PAGE and HPLC analysis
- 产品形式:
- Lyophilized
- 免责声明:
- *本产品仅供科研实验使用,不得用于临床诊断。*
- 说明书:
NNT-1/BCSF-3 is a neurotrophic factor with B-cell stimulating capabilities. Expressed in lymph nodes and spleen, NNT-1/BCSF-3 binds and activates glycoprotein 130 (gp130) and leukemia inhibitory factor receptor member beta (LIFR-beta) and induces tyrosine phosphorylation of these receptors. In vitro, it supports the survival of chick embryo motor and sympathetic neurons. In mice, NNT-1/BCSF-3 induces serum amyloid A, causes body weight loss and B cell hyperplasia associated with increased in serum IgG and IgM. Recombinant human NNT-1/BCSF-3 is a 22.4 kDa protein containing 199 amino acid residues.