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Recombinant SARS-CoV-2 (2019-nCoV) NSP8
Recombinant SARS-CoV-2 (2019-nCoV) NSP8
- 中文名称：
- Recombinant SARS-CoV-2 (2019-nCoV) NSP8
- 英文名称：
- Recombinant SARS-CoV-2 (2019-nCoV) NSP8
- 品牌：
- AAA Biotech
- 品牌介绍：
- AAA Biotech专注于为全球生命科学研究提供高品质的蛋白质研究工具，核心产品包括经严格验证的抗体、重组蛋白及ELISA试剂盒。
- 货号：
- AAA41019
- 规格：
- 0.05 mg|0.1 mg|1 mg|2x1 mg|3x1 mg
- 保存建议：
- Store at -20 to -80°C for twelve months from the date of receipt.
Use a manual defrost freezer and avoid repeated freeze thaw cycles.
- 货期：
- 6-8周
- 纯度：
- >90% as determined by SDS-PAGE
- 产品形式：
- Supplied as a solution form in PBS, pH 7.5 or as lyophilized from PBS, pH 7.5
- 免责声明：
- *本产品仅供科研实验使用，不得用于临床诊断。*
- 说明书：
Recombinant SARS-CoV-2 NSP8 is produced by E.coli expression system and the target gene encoding Ala1-Gln198 is expressed with N-His Tag
Background
Cleavage by the viral main protease, 3CLpro results in generating the nsp8 protein, The nsp8 protein has been shown to associate with several other nsps and to colocalize with these nsps in cytoplasmic complexes that are important for viral RNA synthesis. It forms a hexadecamer with nsp7 (8 subunits of each) that may participate in viral replication by acting as a primase. Alternatively, may synthesize substantially longer products than oligonucleotide primers. Nsp8 was shown to have RNA-dependent RNA polymerase (RdRp) activity that could be involved in producing primers utilized by nsp12 which is normally accepted to be the RdRp for SARS-CoV.
