
-
ViraDuctin AAV Transduction Kit (50 Transductions)
ViraDuctin AAV Transduction Kit (50 Transductions)
- 中文名称:
- ViraDuctin AAV Transduction Kit (50 Transductions)
- 英文名称:
- ViraDuctin AAV Transduction Kit (50 Transductions)
- 品牌:
- AAA Biotech
- 品牌介绍:
- AAA Biotech专注于为全球生命科学研究提供高品质的蛋白质研究工具,核心产品包括经严格验证的抗体、重组蛋白及ELISA试剂盒。
- 货号:
- AAA44622
- 规格:
- 50 Transductions|2x50 Transductions|3x50 Transductions|4x50 Transductions|5x50 Transductions
- 保存建议:
- Store kit components at -20 degree C until their expiration dates. Avoid multiple freeze/thaws by aliquoting.
- 货期:
- 6-8周
- 纯度:
- N/A
- 产品形式:
- N/A
- 免责声明:
- *本产品仅供科研实验使用,不得用于临床诊断。*
- 说明书:
Background: The viral system includes vectors developed from retrovirus (RV), adenovirus (AdV), adeno-associated virus (AAV), lentivirus (LV), and herpes simplex virus (HSV). AAV belongs to the family of Parvoviridae, a group of viruses among the smallest of single-stranded and non-enveloped DNA viruses. There are eight different AAV serotypes reported to date. Recombinant AAV-2 is the most common serotype used in gene delivery, and can be produced at high titers with a helper virus or AAV Helper-Free System. AAV can infect both dividing and non-dividing cells and can be maintained in the human host cell, creating the potential for genome integration. Because AAV is a naturally defective virus, requiring provision of several factors in trans for productive infection, it is considered the safest viral vector to use. These factors make AAV an attractive vector for gene therapy. The AAV transduction process includes viral binding and entry, intracellular trafficking, nuclear transport, and viral second strand DNA synthesis. The viral second strand DNA synthesis has been shown to be the rate limiting step, which leads to inefficient transduction by AAV vectors.