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Recombinant Bee Venom Phospholipase A2
Recombinant Bee Venom Phospholipase A2
- 中文名称:
- Recombinant Bee Venom Phospholipase A2
- 英文名称:
- Recombinant Bee Venom Phospholipase A2
- 品牌:
- AAA Biotech
- 品牌介绍:
- AAA Biotech专注于为全球生命科学研究提供高品质的蛋白质研究工具,核心产品包括经严格验证的抗体、重组蛋白及ELISA试剂盒。
- 货号:
- AAA47957
- 规格:
- 0.1 mg|0.5 mg|1 mg|2x1 mg|3x1 mg
- 保存建议:
- Stable for at least 1 year if stored at or below -20 degree C. Avoid repeated freeze-thaw cycles.
- 货期:
- 6-8周
- 纯度:
- Purified by proprietary chromatography technique. Purity is >90% as determined by 105 SDS-PAGE.
- 产品形式:
- Clear Liquid; Solution in 20mM Tris-HCL, pH 7.2, 1.5M urea, and 50% glycerol.
- 免责声明:
- *本产品仅供科研实验使用,不得用于临床诊断。*
- 说明书:
Description: Recombiant protein produced in E. coli coressponds to aa 26-162 of the protein. It includes a 6XHis-tag at the C-terminus.
Background: Bee venom phospholipase A2 (BVPLA2) is the primary allergen in bee venom. It is a hydrolytic enzyme which cleaves the sn-2-acyl bond of phospholipids at the lipid/water interface. BV-PLA2 is a 14-16kDa glycoprotein consisting of 134 amino acids with a single carbohydrate side chain at residue Asn13. BV-PLA2 displays 3 peptide T-cell epitopes and 1 glycopeptide T-cell epitope which are recognized by allergic and non-allergic bee venom-sensitized individuals. BVPLA2 elicits IgE-mediated allergic responses in allergic individuals.
Recombinant BV-PLA2 produced in E. coli corresponds to aa 26-162 of this enzyme.