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Gankyrin, 1-226aa, Human,E Coli
Gankyrin, 1-226aa, Human,E Coli
- 中文名称:
- Gankyrin, 1-226aa, Human,E Coli
- 英文名称:
- Gankyrin, 1-226aa, Human,E Coli
- 品牌:
- AAA Biotech
- 品牌介绍:
- AAA Biotech专注于为全球生命科学研究提供高品质的蛋白质研究工具,核心产品包括经严格验证的抗体、重组蛋白及ELISA试剂盒。
- 货号:
- AAA48512
- 规格:
- 0.02 mg|0.1 mg|5x0.02 mg|0.5 mg|5x0.1 mg
- 保存建议:
- Can be stored at 4°C short term (1-2 weeks).
For long term storage, aliquot and store at -20°C or -70° C.
Avoid repeated freezing and thawing cycles.
- 货期:
- 6-8周
- 纯度:
- > 95% by SDS-PAGE
- 产品形式:
- Liquid in phosphate buffered saline (pH 7.4), 10% glycerol
- 免责声明:
- *本产品仅供科研实验使用,不得用于临床诊断。*
- 说明书:
Gankyrin is an oncoprotein commonly overexpressed in most hepatocellular carcinomas. Gankyrin interacts with S6 ATPase of the 19S regulatory particle of the 26S proteasome. It is known to play a role in the regulation of the phosphorylation of the retinoblastoma protein by CDK4, and to enhance the ubiquitinylation of p53 by MDM2. Gankyrin consists of 7 ankyrin repeats and is structurally similar to I kappa Bs. Recombinant human Gankyrin was expressed in E Coli and purified by conventional chromatography techniques.