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Bcl-2, 1-211aa, Human, His tag, E Coli
Bcl-2, 1-211aa, Human, His tag, E Coli
- 中文名称：
- Bcl-2, 1-211aa, Human, His tag, E Coli
- 英文名称：
- Bcl-2, 1-211aa, Human, His tag, E Coli
- 品牌：
- AAA Biotech
- 品牌介绍：
- AAA Biotech专注于为全球生命科学研究提供高品质的蛋白质研究工具，核心产品包括经严格验证的抗体、重组蛋白及ELISA试剂盒。
- 货号：
- AAA48514
- 规格：
- 0.02 mg|0.1 mg|2x0.1 mg|5x0.02 mg|3x0.1 mg
- 保存建议：
- Can be stored at 4 degree C short term (1-2 weeks).
For long term storage, aliquot and store at -20 degree C or -70 degree C.
Avoid repeated freezing and thawing cycles.
- 货期：
- 6-8周
- 纯度：
- > 90% by SDS-PAGE
- 产品形式：
- Liquid. In 20 mM Tris-HCl Buffer (pH 8.0) containing 20% glycerol 2 mM DTT
- 免责声明：
- *本产品仅供科研实验使用，不得用于临床诊断。*
- 说明书：
Bcl-2, also known as B-cell lymphoma protein 2 alpha, is an anti-apoptotic protein located primarily in the outer mitochondrial membrane that blocks the apoptotic death of some cells such as lymphocytes. BCL-2 is thought to regulate cell death by controlling the mitochondrial membrane permeability during apotosis. Bcl-2 exerts its anti-apoptotic function through inhibiting caspase activity either by preventing the release of cytochrome c from the mitochondria and/or by binding to the apoptosis-activating factor (APAF-1). The Bcl-2 gene has been related with a number of cancers, including melanoma, breast, prostate, and lung carcinomas, as well as schizophrenia and autoimmunity. Recombinant Bcl-2 protein was expressed in E Coli and purified by conventional chromatography, after refolding of the isolated inclusion bodies in a renaturation buffer.
