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GZMB, 19-247aa, Human, His-tag, Baculovirus (Bioactivity Validated)
GZMB, 19-247aa, Human, His-tag, Baculovirus (Bioactivity Validated)
- 中文名称:
- GZMB, 19-247aa, Human, His-tag, Baculovirus (Bioactivity Validated)
- 英文名称:
- GZMB, 19-247aa, Human, His-tag, Baculovirus (Bioactivity Validated)
- 品牌:
- AAA Biotech
- 品牌介绍:
- AAA Biotech专注于为全球生命科学研究提供高品质的蛋白质研究工具,核心产品包括经严格验证的抗体、重组蛋白及ELISA试剂盒。
- 货号:
- AAA48973
- 规格:
- 0.01 mg|0.02 mg|0.05 mg|0.1 mg|0.25 mg
- 保存建议:
- Can be stored at 4°C short term (1 week).
For long term storage, aliquot and store at -20°C or -80°C.
Avoid repeated freezing and thawing cycles.
- 货期:
- 6-8周
- 纯度:
- > 95% by SDS-PAGE
- 产品形式:
- Liquid. In phosphate buffered saline (pH 7.4) containing 20% glycerol, 1mM DTT.
- 免责声明:
- *本产品仅供科研实验使用,不得用于临床诊断。*
- 说明书:
GZMB, also known as granzyme B isoform 1, is member of the granzyme subfamily of proteins, part of the peptidase S1 family of serine proteases. Tis protein is secreted by natural killer (NK) cells and cytotoxic T lymphocytes (CTLs) and proteolytically processed to generate the active protease, which induces target cell apoptosis. Also, it processes cytokines and degrades extracellular matrix proteins, and these roles are implicated in chronic inflammation and wound healing. Expression of this gene may be elevated in human patients with cardiac fibrosis. Recombinant human GZMB, fused to His-tag at C-terminus, was expressed in insect cell and purified by using conventional chromatography techniques.