
-
Recombinant human CD26/DPP4 protein
Recombinant human CD26/DPP4 protein
- 中文名称:
- Recombinant human CD26/DPP4 protein
- 英文名称:
- Recombinant human CD26/DPP4 protein
- 品牌:
- AAA Biotech
- 品牌介绍:
- AAA Biotech专注于为全球生命科学研究提供高品质的蛋白质研究工具,核心产品包括经严格验证的抗体、重组蛋白及ELISA试剂盒。
- 货号:
- AAA48980
- 规格:
- 0.01 mg|0.02 mg|0.05 mg|0.1 mg|0.25 mg
- 保存建议:
- Can be stored at +2C to +8C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.
- 货期:
- 6-8周
- 纯度:
- > 95% by SDS-PAGE
- 产品形式:
- Liquid in. Phosphate-Buffered Saline (pH7.4) containing 10% glycerol
- 免责声明:
- *本产品仅供科研实验使用,不得用于临床诊断。*
- 说明书:
DPP4, dipeptidyl peptidase-4 is a complex enzyme expressed on the surface of most cell types and is a serine exopeptidase that cleaves x-proline dipeptides from the N-terminus of polypeptides. DPP4 protein is associated with intracellular signal transduction, apoptosis and plays an important role in tumor biology. There are at least 63 substrates which can bind specifically to DPP4 enzyme including growth factors, chemokines, neuro peptides. Furthermore, DPP4 plays a major role in glucose metabolism by cleaving incretins such as glucose-dependent insulinotropic polypeptide (GIP) and glucagon-like peptide-1 (GLP-1). Middle East respiratory syndrome coronavirus has been found to bind to DPP4. It is found on the surface of cells in the airways and kidneys. Recombinant human DPPIV/CD26, fused to hIgG-tag at C-terminus, was expressed in HEK293 cell and purified by using conventional chromatography techniques.